Structure
(Human PD-L1 inhibitor III, CAS 2135542-84-4)
ML338 biochemical
ML338
Purity
98%
Synonyms
ML338; N/A; ML338 biochemical
Purity/Purification
98%
CAS
1630160-25-6
Targets&IC50
non-replicatingMycobacterium tuberculosis bacilli:1 uM (IC90), non-replicatingMycobacterium tuberculosis bacilli:4 uM (IC99)
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
ML338 (0-50 uM) has potency and selectivity against non-replicating M. tuberculosis with an IC 90 of 1 uM. Additionally, ML338 have an IC 99 against non-replicating M. tuberculosis (4 uM) which is excellent relative to current TB drugs[1]. ML338 (0-50 uM; 48 hours) shows no toxicity to J774 macrophage cells up to 50 uM, the highest concentration[1]. ML338 is against the non-replicating M. tuberculosis with IC 90 and IC 99 velues of 1 uM and 4 uM, respectively by CFU. Additionally, it against the replicating M. tuberculosis with IC 90 and IC 99 velues of 62 uM and 62 uM, respectively by CFU[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Human PD-L1 inhibitor III, CAS 2135542-84-4)
Structure
(Human PD-L1 inhibitor III, CAS 2135542-84-4)
Structure
(Human PD-L1 inhibitor III, CAS 2135542-84-4)
Structure
(Human PD-L1 inhibitor III, CAS 2135542-84-4)
Related Product Information for ML338 biochemical
ML338 is a selective small molecule inhibitor probe of non-replicating Mycobacterium tuberculosis bacilli and is against the non-replicating M. tuberculosis with IC 90 and IC 99 values of 1 uM and 4 uM, respectively by CFU. ML338 is a invaluable tool for identifying both essential functions and vulnerabilities of the M. tuberculosis bacilli in the nutrient deprivation states. ML338 can be used for the study of M. tuberculosis chemotherapy.
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Product Notes
The ML338 (Catalog #AAA227837) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ML338, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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