Structure
(BRD4-IN-2, CAS 2679925-55-2)
Msr-Ratio biochemical
Msr-Ratio
Purity
98%
Synonyms
Msr-Ratio; N/A; Msr-Ratio biochemical
Purity/Purification
98%
CAS
2290635-22-0
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Msr-Ratio is converted to its corresponding sulfide form by methionine sulfoxide reductase. Msr-Ratio displays favorable properties such as a nearly 400-fold fluorescence change, fast response rate (<30 min), large Stokes shift (120 nm), and green emission (550 nm)[1]. There is a very weak background signal in live HL60 cells after the addition of Msr-Ratio. As the Msr-Ratio (10 uM) incubation time increased in cells from 0 to 8 h, the fluorescence signal constantly strengthened[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(BRD4-IN-2, CAS 2679925-55-2)
Structure
(BRD4-IN-2, CAS 2679925-55-2)
Structure
(BRD4-IN-2, CAS 2679925-55-2)
Structure
(BRD4-IN-2, CAS 2679925-55-2)
Related Product Information for Msr-Ratio biochemical
Msr-Ratio (Msr-green) is a ratiometric fluorescent probe of methionine sulfoxide reductase (lambdaex=375 nm, lambdaem=550 nm). Msr-Ratio is used for monitoring the enzyme activity in vitro and in live cells.
References
1. Sabnis RW. Substituted 2,3-Benzodiazepines Derivatives as Bromodomain BRD4 Inhibitors. ACS Med Chem Lett. 2021 Sep 28;12(10):1530-1531.
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Product Notes
The Msr-Ratio (Catalog #AAA228296) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Msr-Ratio, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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