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product-image-AAA227769_STRUCTURE13.gif Structure (HaXS8, CAS 2080306-25-6)

Pramlintide Biochemical

Pramlintide

Purity
98%
Synonyms
Pramlintide; N/A; Pramlintide biochemical
Ordering
Purity/Purification
98%
CAS
151126-32-8
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Pramlintide inhibits the growth of HCT-116 and HT-29 in a dose-dependent manner, with higher efficacy against the latter (IC 50 s of 48.67 and 9.10 ug/mL, respectively)[1]. The addition of 5, 10, and 20 ug/mL of Pramlintide to HCT-116 and HT-29 with 5-fluorouracil, Oxaliplatin, or Irinotecan induces the antiproliferative effect synergistically[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years

Structure

(HaXS8, CAS 2080306-25-6)

product-image-AAA227769_STRUCTURE13.gif Structure (HaXS8, CAS 2080306-25-6)

Structure

(HaXS8, CAS 2080306-25-6)

product-image-AAA227769_STRUCTURE15.gif Structure (HaXS8, CAS 2080306-25-6)
Related Product Information for Pramlintide biochemical
Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer.
References
1. Erhart D, et, al. Chemical development of intracellular protein heterodimerizers. Chem Biol. 2013 Apr 18; 20(4): 549-57.
2. Saha I, et, al. Dynamics of the HIV Gag Lattice Detected by Localization Correlation Analysis and Time-Lapse iPALM. Biophys J. 2020 Aug 4; 119(3): 581-592.

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Product Notes

The Pramlintide (Catalog #AAA227769) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Pramlintide, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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