Structure
(Benzyl-PEG6-Ots, CAS 129086-11-9)
RC363 biochemical
RC363
Purity
98%
Synonyms
RC363; N/A; RC363 biochemical
Purity/Purification
98%
Solubility
Ethanol:PBS (pH 7.2)(1:1): Insouble
Ethanol: 30 mg/mL
DMF: 30 mg/mL
PBS (pH 7.2): Insouble
DMSO: 30 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
Ethanol: 30 mg/mL
DMF: 30 mg/mL
PBS (pH 7.2): Insouble
DMSO: 30 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Benzyl-PEG6-Ots, CAS 129086-11-9)
Structure
(Benzyl-PEG6-Ots, CAS 129086-11-9)
Structure
(Benzyl-PEG6-Ots, CAS 129086-11-9)
Structure
(Benzyl-PEG6-Ots, CAS 129086-11-9)
Related Product Information for RC363 biochemical
RC363 is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol.1It reduces 2,2-diphenyl-1-picrylhydrazyl radicals by approximately 40% in a cell-free assay when used at a concentration of 25 uM. RC363 prevents glutamate-induced toxicity in HT22 cultured hippocampal cells (IC50= 234.5 nM) but does not reduce oxidant levels in these cells. It increases the levels of glutathione peroxidase 1 (GPX1) and the activity of GPX in glutamate-challenged HT22 cells when used at a concentration of 3 uM. RC363 inhibits ferroptosis induced by the GPX4 inhibitor RSL3 in HT22 cells (IC50= 173.6 nM).
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Product Notes
The RC363 (Catalog #AAA227169) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RC363, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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