Structure
(SENP1-IN-2, CAS 2416910-70-6)
RIP2 Kinase Inhibitor 4 Biochemical | RIP2 biochemical
RIP2 Kinase Inhibitor 4
Purity
98%
Synonyms
RIP2 Kinase Inhibitor 4; N/A; RIP2 biochemical
Purity/Purification
98%
CAS
2126803-41-4
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
The initial in vivo assessment of RIP2 Kinase Inhibitor 4 (Compound 20) in rats dosed at 0.5 mg/kg SC demonstrated high levels of RIPK2 degradation and inhibition of MDP-stimulated TNFalpha release at the final 48 h time point[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(SENP1-IN-2, CAS 2416910-70-6)
Structure
(SENP1-IN-2, CAS 2416910-70-6)
Structure
(SENP1-IN-2, CAS 2416910-70-6)
Structure
(SENP1-IN-2, CAS 2416910-70-6)
Related Product Information for RIP2 biochemical
RIP2 Kinase Inhibitor 4 is a potent and selective RIPK2 PROTAC. RIP2 Kinase Inhibitor 4 effectively degrades RIPK2 (pIC 50 of 8) and inhibits the release of related TNF-alpha.
References
1. Li, Yiliang, et al. Preparation of ursolic acid derivatives useful as SENP1 inhibitors and tumor radiosensitizer. CN110627860A.
Similar Products
Product Notes
The RIP2 (Catalog #AAA228137) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RIP2 Kinase Inhibitor 4, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.