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product-image-AAA228945_STRUCTURE13.png Structure (BLU-945, CAS 2660250-10-0)

Streptokinase Biochemical

Streptokinase

Purity
98%
Synonyms
Streptokinase; N/A; BLU 945; BLU945; Streptokinase biochemical
Ordering
Purity/Purification
98%
CAS
9002-01-1
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Sreptokinase (6000 IU/kg in 3 ml of saline; intracoronary; infused at 0.05 ml/min for 60 minutes beginning 30 minutes before reperfusion) maintains reperfusion coronary blood flow through a critical stenosis at a rate similar to baseline levels[2].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years

Structure

(BLU-945, CAS 2660250-10-0)

product-image-AAA228945_STRUCTURE13.png Structure (BLU-945, CAS 2660250-10-0)

Structure

(BLU-945, CAS 2660250-10-0)

product-image-AAA228945_STRUCTURE15.png Structure (BLU-945, CAS 2660250-10-0)
Related Product Information for Streptokinase biochemical
Streptokinase is a bacteria-derived protein and a plasminogen activator. Streptokinase is widely used for the research of the blood-clotting disorders. Streptokinase improves reperfusion blood flow after coronary artery occlusion.
Product Categories/Family for Streptokinase biochemical
References
1. John Emmerson Campbell, et al. Inhibitors of mutant forms of egfr. Patent WO2021133809A1.
2. Sun Min Lim, et al. BLU-945, a fourth-generation, potent and highly selective epidermal growth factor receptor tyrosine kinase inhibitor with intracranial activity, demonstrates robust in vivo anti-tumor activity in models of osimertinib-resistant non-sma
3. Meredith S Eno, et al. Discovery of BLU-945, a Reversible, Potent, and Wild-Type-Sparing Next-Generation EGFR Mutant Inhibitor for Treatment-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2022 Jul 28;65(14):9662-9677.
4. Elaine Shum. et al. A phase 1/2 study of BLU-945 in patients with common activating EGFRmutant non-small cell lung cancer (NSCLC)(SYMPHONY trial-in-progress)

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Product Notes

The Streptokinase (Catalog #AAA228945) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Streptokinase, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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