Transdermal Peptide Disulfide TFA Biochemical

Transdermal Peptide Disulfide TFA

Cat. Num. AAA227336

• Purity: 98%
• Synonyms: Transdermal Peptide Disulfide TFA; N/A; Transdermal Peptide Disulfide TFA biochemical

• Purity/Purification: 98%

• Solubility: H2O: 100 mg/mL (85.09 mM); <1mg/ml refers to the product slightly soluble or insoluble
• In vitro: In the presence of Transdermal Peptide Disulfide, because of the specific binding of Transdermal Peptide Disulfide to ATP1B1, cells will upregulate the level of ATP1B1 to maintain function and structure; as a result, the expression of ATP1B1 increases. However, as time goes on, some Transdermal Peptide Disulfide molecules may be transported into cells by endocytosis; consequently, the expression of ATP1B1 then decreases. The interaction between Transdermal Peptide Disulfide and ATP1B1 changes not only the expression of ATP1B1, but also the localization of ATP1B1 and then the structure of the epidermal layer. This interaction can be attenuated by inhibitors or competitors, which would result in the reduced delivery of macromolecular drugs across the skin[1].
• Preparation and Storage: Powder: -20 degree C for 3 years; In solvent: -80 degree C for 2 years

Structure

(3,11,15,23-Tetraoxo-27?-lanosta-8,16-dien-26-oic acid, CAS 1427189-02-3)

Structure

(3,11,15,23-Tetraoxo-27?-lanosta-8,16-dien-26-oic acid, CAS 1427189-02-3)

Related Product Information for Transdermal Peptide Disulfide TFA biochemical

Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) is a 11-amino acid peptide, binds to Na+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide TFA can enhance the transdermal delivery of many macromolecules[1].

References

1. Liaw CC, et, al. Anti-inflammatory lanostanoids and lactone derivatives from Antrodia camphorate. J Nat Prod. 2013 Apr 26;76(4):489-94.