Structure
(3-Keto petromyzonol, CAS 359436-56-9)
UNC2399 Biochemical
UNC2399
Purity
98%
Synonyms
UNC2399; N/A; UNC2399 biochemical
Purity/Purification
98%
CAS
2412791-72-9
Targets&IC50
EZH2:17 nM (IC50)
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
UNC2399 (1-1000 nM) displays high in vitro potency (IC 50 =17+/-2 nM) in the EZH2 radioactive biochemical assay[1]. UNC2399 (100 uM) enriches EZH2 from HEK293T cell lysates[1].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(3-Keto petromyzonol, CAS 359436-56-9)
Structure
(3-Keto petromyzonol, CAS 359436-56-9)
Structure
(3-Keto petromyzonol, CAS 359436-56-9)
Structure
(3-Keto petromyzonol, CAS 359436-56-9)
Related Product Information for UNC2399 biochemical
UNC2399, a biotinylated UNC1999, is a selective EZH2 degrader, maintaining high in vitro potency for EZH2, with an IC 50 of 17 nM.
References
1. Yu-Wen Chung-Davidson, et al. Pheromonal Bile Acid 3-ketopetromyzonol Sulfate Primes the Neuroendocrine System in Sea Lamprey. BMC Neurosci. 2013 Jan 20;14:11.
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Product Notes
The UNC2399 (Catalog #AAA228412) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "UNC2399, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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