BPI blocking peptide
BPI Antibody (Center) Blocking Peptide
Gene Names
BPI; rBPI; BPIFD1
Synonyms
BPI; N/A; BPI Antibody (Center) Blocking Peptide; Bactericidal permeability-increasing protein; CAP 57; BPI blocking peptide
Clone Number
80311208
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human BPI. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
487
Cellular Location
Secreted. Cytoplasmic granule membrane. Note: Membrane-associated in polymorphonuclear Leukocytes (PMN) granules
Function
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Tissue Location
Restricted to cells of the myeloid series.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for BPI blocking peptide
BPI encodes a lipopolysaccaride binding protein. It is associated with human neutrophil granules and has a bactericidal activity on gram-negative organisms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Bactericidal permeability-increasing protein
NCBI Official Synonym Full Names
bactericidal/permeability-increasing protein
NCBI Official Symbol
BPI
NCBI Official Synonym Symbols
rBPI; BPIFD1
NCBI Protein Information
bactericidal permeability-increasing protein
UniProt Protein Name
Bactericidal permeability-increasing protein
UniProt Gene Name
BPI
UniProt Synonym Gene Names
BPI
UniProt Entry Name
BPI_HUMAN
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Product Notes
The BPI bpi (Catalog #AAA290818) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BPI, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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