Phospho-MERTK Blocking Peptide | MERTK blocking peptide
Phospho-MERTK Peptide
Gene Names
Mertk; rdy
Applications
Immunocompetition, Immunodepletion
Synonyms
Phospho-MERTK; N/A; Phospho-MERTK Peptide; c MER antibody;c mer proto oncogene tyrosine kinase antibody;Eyk antibody;MER antibody;MERPEN antibody;Mertk antibody;MERTK c-mer proto-oncogene tyrosine kinase antibody;MGC133349 antibody;nmf12 antibody;Nyk antibody;Proto oncogene tyrosine protein kinase MER antibody;Receptor tyrosine kinase MerTK antibody;RP38 antibody;STK kinase antibody;Tyrosine-protein kinase Mer antibody; MERTK blocking peptide
Form/Format
Synthetic Peptide
Sequence Positions
CCKKIYPSGDYPYPRQG
Sequence Length
994
Applicable Applications for MERTK blocking peptide
Immunocompetition, Immunodepletion
Immunogen Description
Synthetic peptide corresponding to amino acids 746-757 of Human MERTK.
Molecular Function
Kinase, Receptor, Transferase, Tyrosine-protein kinase
Structure
Interacts (upon activation) with TNK2; stimulates TNK2 autophosphorylation. Interacts (via N-terminus) with extracellular ligands LGALS3, TUB, TULP1 and GAS6. Interacts with VAV1 in a phosphotyrosine-independent manner.
Subcellular Location
Membrane; Single-pass type I membrane protein
Preparation and Storage
-20 degree C for long term storage
Related Product Information for MERTK blocking peptide
Antigenic Blocking Peptide Phosphorylated Tyrosine-protein kinase Mer
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules.
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
tyrosine-protein kinase Mer
NCBI Official Synonym Full Names
MER proto-oncogene, tyrosine kinase
NCBI Official Symbol
Mertk
NCBI Official Synonym Symbols
rdy
NCBI Protein Information
tyrosine-protein kinase Mer
UniProt Protein Name
Tyrosine-protein kinase Mer
UniProt Gene Name
Mertk
UniProt Synonym Gene Names
Mer
UniProt Entry Name
MERTK_RAT
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Product Notes
The MERTK mertk (Catalog #AAA76031) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is CCKKIYPSGDYPYPRQG. AAA Biotech's Phospho-MERTK can be used in a range of immunoassay formats including, but not limited to, Immunocompetition, Immunodepletion. Researchers should empirically determine the suitability of the MERTK mertk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phospho-MERTK, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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