Application Data
(Image: Detection of Bmi1 protein in skeletal muscle.)
Bmi1 Antibody | anti-Bmi1 antibody
Bmi1, Affinity Purified Antibody, Rabbit
Reactivity
Bovine, Cat, Chicken, Human, Mouse, Primate, Rat, Rabbit, Zebrafish
Applications
Western Blot, Immunofluorescence, Immunocytochemistry
Synonyms
Bmi1; N/A; Bmi1, Affinity Purified Antibody, Rabbit; anti-Bmi1 antibody
Reactivity
Bovine, Cat, Chicken, Human, Mouse, Primate, Rat, Rabbit, Zebrafish
Form/Format
Affinity Purified - Liquid
Sequence Length
469
Applicable Applications for anti-Bmi1 antibody
WB (Western Blot), IF (Immunofluorescence), ICC (Immunocytochemistry)
Type Info
Rabbit IgG
Immunogen
A synthetic peptide made to an internal region (within residues 1-100) of the human Bmi1 protein. [Swiss-Prot# P35226].
Application Data
(Image: Detection of Bmi1 protein in skeletal muscle.)
Application Data
(Image: Detection of Bmi1 protein in skeletal muscle.)
Application Data
(Image: Bmi1 staining in Hela cells.)
Application Data
(Image: Bmi1 staining in Hela cells.)
Related Product Information for anti-Bmi1 antibody
Bmi1 induces telomerase activity and immortalizes human mammary epithelial cells. Bmi1 extends the replicative life span of human fibroblasts by suppressing the p16-dependent senescence pathway. It has also been termed an oncogene with aberrant expression in various carcinomas. It has been shown to be a negative regulator of p19Arf, Ink4a (p14Arf) and tp53 known tumor repressors. Ablation of Bmi1 is required for short term survival of cancer cells.
In addition, Bmi1 expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.
In addition, Bmi1 expression promotes HSC self-renewal. These findings highlight the importance of epigenetic regulation in HSC self-renewal and identify PcG genes as potential targets for therapeutic HSC manipulation.
Product Categories/Family for anti-Bmi1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
COMMD3-BMI1 read-through protein
NCBI Official Synonym Full Names
COMMD3-BMI1 readthrough
NCBI Official Symbol
COMMD3-BMI1
NCBI Protein Information
COMMD3-BMI1 read-through protein
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Product Notes
The Bmi1 (Catalog #AAA76450) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Bmi1, Affinity Purified Antibody, Rabbit reacts with Bovine, Cat, Chicken, Human, Mouse, Primate, Rat, Rabbit, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's Bmi1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence), ICC (Immunocytochemistry). Researchers should empirically determine the suitability of the Bmi1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Bmi1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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