Application Data
(Image: Detection of CDR2 in HeLa whole cell lysates.)
CDr2 Antibody | anti-CDR2 antibody
CDr2, Polyclonal Antibody, Rabbit
Gene Names
CDR2; Yo; CDR62
Reactivity
Bovine, Human, Mouse, Primate
Applications
Western Blot, Immunohistochemistry
Synonyms
CDr2; N/A; CDr2, Polyclonal Antibody, Rabbit; anti-CDR2 antibody
Reactivity
Bovine, Human, Mouse, Primate
Form/Format
Affinity Purified - Liquid
Sequence Length
454
Applicable Applications for anti-CDR2 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Type Info
Rabbit IgG
Immunogen
A synthetic peptide made to a C-terminal region of the human CDR2 protein. [Swiss-prot# Q01850].
Application Data
(Image: Detection of CDR2 in HeLa whole cell lysates.)
Application Data
(Image: Detection of CDR2 in HeLa whole cell lysates.)
Application Data
(Image: CDR2 staining of Purkinje neurons in the Human cerebellum)
Application Data
(Image: CDR2 staining of Purkinje neurons in the Human cerebellum)
Related Product Information for anti-CDR2 antibody
Using anti-Yo antibodies, three genes have been cloned (CDR 1-3). CDR2 Cerebellar degeneration related protein 2) suppresses the transcriptional activity and DNA binding of nuclear factor-kappa B by an unknown mechanism. The neuron specific expression of CDR2 is regulated by a post-transcriptional mechanism.
CDR2 is an onconeuronal antigen; i.e. an antigen that is expressed by systemic tumors and elicits an immune response that may develop into an autoimmune neuronal degeneration. Paraneoplastic cerebellar degeneration (PCD) is a disorder in which breast or ovarian tumors express CDR2, which normally is expressed in cerebellar Purkinje neurons.
CDR2 is an onconeuronal antigen; i.e. an antigen that is expressed by systemic tumors and elicits an immune response that may develop into an autoimmune neuronal degeneration. Paraneoplastic cerebellar degeneration (PCD) is a disorder in which breast or ovarian tumors express CDR2, which normally is expressed in cerebellar Purkinje neurons.
Product Categories/Family for anti-CDR2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,855 Da
NCBI Official Full Name
cerebellar degeneration-related protein 2
NCBI Official Synonym Full Names
cerebellar degeneration related protein 2
NCBI Official Symbol
CDR2
NCBI Official Synonym Symbols
Yo; CDR62
NCBI Protein Information
cerebellar degeneration-related protein 2
UniProt Protein Name
Cerebellar degeneration-related protein 2
UniProt Gene Name
CDR2
UniProt Synonym Gene Names
PCD17
UniProt Entry Name
CDR2_HUMAN
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Product Notes
The CDR2 cdr2 (Catalog #AAA76463) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CDr2, Polyclonal Antibody, Rabbit reacts with Bovine, Human, Mouse, Primate and may cross-react with other species as described in the data sheet. AAA Biotech's CDr2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CDR2 cdr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDr2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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