FCM/FACS (Flow Cytometry)
Calmodulin1 Recombinant Protein | CALM1 recombinant protein
Calmodulin1 recombinant protein
Gene Names
CALM1; caM; CAMI; PHKD; CPVT4; DD132; CALML2
Applications
Western Blot
Synonyms
Calmodulin1; N/A; Calmodulin1 recombinant protein; CALM1; CALML2; CAMI; DD132; PHKD; Calmodulin 1 Protein; CALM1 recombinant protein
Host
E Coli
Form/Format
Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Sequence Length
4268
Applicable Applications for CALM1 recombinant protein
WB (Western Blot), Kinase Assay
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
FCM/FACS (Flow Cytometry)
FCM/FACS (Flow Cytometry)
SDS-PAGE
SDS-PAGE
Related Product Information for CALM1 recombinant protein
Recombinant full-length human calmodulin1 was expressed in E.coli cells using an N-terminal His tag. The gene accession number is NM_006888.
Scientific Background: Calmodulin 1 is a member of calcium-modulated proteins which is present in the cytosol and on membranes facing the cytosol and has a high affinity for calcium. Calmodulin 1 has 4 calcium-binding domains and plays a role in cell growth, cell cycle, signal transduction and the synthesis and release of neurotransmitters. Calmodulin can bind to the epidermal growth factor receptor at its cytosolic juxtamembrane region and this inhibits its tyrosine kinase activity. A number of other proteins including HSP70 have been shown to interact with Calmodulin 1 in a cell-phase-specific manner.
Scientific Background: Calmodulin 1 is a member of calcium-modulated proteins which is present in the cytosol and on membranes facing the cytosol and has a high affinity for calcium. Calmodulin 1 has 4 calcium-binding domains and plays a role in cell growth, cell cycle, signal transduction and the synthesis and release of neurotransmitters. Calmodulin can bind to the epidermal growth factor receptor at its cytosolic juxtamembrane region and this inhibits its tyrosine kinase activity. A number of other proteins including HSP70 have been shown to interact with Calmodulin 1 in a cell-phase-specific manner.
Product Categories/Family for CALM1 recombinant protein
References
1. Li, H. et al: Endogenous calmodulin interacts with the epidermal growth factor receptor in living cells. FEBS Lett. 2004 Feb 13;559(1-3):175-80.
2. Huang, M. et al: The association of CaM and Hsp70 regulates S-phase arrest and apoptosis in a spatially and temporally dependent manner in human cells. Cell Stress Chaperones. 2009 Jul;14(4):343-53.
2. Huang, M. et al: The association of CaM and Hsp70 regulates S-phase arrest and apoptosis in a spatially and temporally dependent manner in human cells. Cell Stress Chaperones. 2009 Jul;14(4):343-53.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens calmodulin 1 (phosphorylase kinase, delta) (CALM1), mRNA
NCBI Official Synonym Full Names
calmodulin 1 (phosphorylase kinase, delta)
NCBI Official Symbol
CALM1
NCBI Official Synonym Symbols
caM; CAMI; PHKD; CPVT4; DD132; CALML2
NCBI Protein Information
calmodulin; prepro-calmodulin 1; phosphorylase kinase, delta subunit
UniProt Protein Name
Calmodulin
UniProt Gene Name
CALM1
UniProt Synonym Gene Names
CALM; CAM; CAM1; CaM
UniProt Entry Name
CALM_HUMAN
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Product Notes
The CALM1 calm1 (Catalog #AAA72926) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Calmodulin1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), Kinase Assay. Researchers should empirically determine the suitability of the CALM1 calm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calmodulin1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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