Application Data
(Image: Injection of rhHsp70 did not result in overt changes in glial cell activation. Lumbar spinal cord tissue was collected from treated and untreated G93A SOD1 or WT mice on P90. Twenty-five micrograms of protein per lane was loaded into each lane and Western blotting was performed to assess relative levels of GFAP and Iba1. When normalized to actin, quantification of the bands confirmed no change in expression (data not shown). doi:10.1523/JNEUROSCI.4057-07.2007)
Glial Fibrillary Acidic Protein (GFAP) Antibody | anti-GFAP antibody
Glial Fibrillary Acidic Protein (GFAP), Polyclonal Antiserum, Rabbit
Gene Names
GFAP; ALXDRD
Reactivity
Cat, Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry
Synonyms
Glial Fibrillary Acidic Protein (GFAP); N/A; Glial Fibrillary Acidic Protein (GFAP), Polyclonal Antiserum, Rabbit; anti-GFAP antibody
Reactivity
Cat, Human, Mouse, Rat
Form/Format
Whole serum - Liquid
Sequence Length
432
Applicable Applications for anti-GFAP antibody
WB (Western Blot), IHC (Immunohistochemistry), ICC (Immunocytochemistry)
Type Info
Rabbit IgG
Immunogen
Recombinant GFAP and purified bovine GFAP
Application Data
(Image: Injection of rhHsp70 did not result in overt changes in glial cell activation. Lumbar spinal cord tissue was collected from treated and untreated G93A SOD1 or WT mice on P90. Twenty-five micrograms of protein per lane was loaded into each lane and Western blotting was performed to assess relative levels of GFAP and Iba1. When normalized to actin, quantification of the bands confirmed no change in expression (data not shown). doi:10.1523/JNEUROSCI.4057-07.2007)
Application Data
(Image: Injection of rhHsp70 did not result in overt changes in glial cell activation. Lumbar spinal cord tissue was collected from treated and untreated G93A SOD1 or WT mice on P90. Twenty-five micrograms of protein per lane was loaded into each lane and Western blotting was performed to assess relative levels of GFAP and Iba1. When normalized to actin, quantification of the bands confirmed no change in expression (data not shown). doi:10.1523/JNEUROSCI.4057-07.2007)
Application Data
(Image: Mixed neuron-glial cultures stained with rabbit GFAP (red channel) and chicken vimentin (green channel). The fibroblastic cells contain only vimentin and so are green, while astrocytes contain either vimentin and GFAP, so appearing golden, or predominantly GFAP, in which case they appear red. Blue is nuclear DNA stain. Protocol on data-sheet)
Application Data
(Image: Mixed neuron-glial cultures stained with rabbit GFAP (red channel) and chicken vimentin (green channel). The fibroblastic cells contain only vimentin and so are green, while astrocytes contain either vimentin and GFAP, so appearing golden, or predominantly GFAP, in which case they appear red. Blue is nuclear DNA stain. Protocol on data-sheet)
Related Product Information for anti-GFAP antibody
Human GFAP is a 49,749 dalton protein (432 amino acids) expressed in astrocytes. GFAP is an intermediate filament protein and acts as an intracellular structural component of the cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Various mutations of the GFAP gene in humans produce Alexander's disease, one of the leukodystrophies.
Antibodies to GFAP are therefore very useful as markers of astrocytic cells and neural stem cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP.
Antibodies to GFAP are therefore very useful as markers of astrocytic cells and neural stem cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP.
Product Categories/Family for anti-GFAP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
49,508 Da
NCBI Official Full Name
Glial fibrillary acidic protein
NCBI Official Synonym Full Names
glial fibrillary acidic protein
NCBI Official Symbol
GFAP
NCBI Official Synonym Symbols
ALXDRD
NCBI Protein Information
glial fibrillary acidic protein
UniProt Protein Name
Glial fibrillary acidic protein
UniProt Gene Name
GFAP
UniProt Synonym Gene Names
GFAP
UniProt Entry Name
GFAP_HUMAN
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Product Notes
The GFAP gfap (Catalog #AAA76528) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Glial Fibrillary Acidic Protein (GFAP), Polyclonal Antiserum, Rabbit reacts with Cat, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Glial Fibrillary Acidic Protein (GFAP) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ICC (Immunocytochemistry). Researchers should empirically determine the suitability of the GFAP gfap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glial Fibrillary Acidic Protein (GFAP), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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