Major centromere autoantigen B (CENPB) Recombinant Protein | CENPB recombinant protein
Recombinant Human Major centromere autoantigen B (CENPB)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Major centromere autoantigen B (CENPB); N/A; Recombinant Human Major centromere autoantigen B (CENPB); CENPB recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-599aa; Full Length of Mature Protein
Sequence
GPKRRQLTFREKSRIIQEVEENPDLRKGEIARRFNIPPSTLSTILKNKRAILASERKYGVASTCRKTNKLSPYDKLEGLLIAWFQQIRAAGLPVKGIILKEKALRIAEELGMDDFTASNGWLDRFRRRHGVVSCSGVARARARNAAPRTPAAPASPAAVPSEGSGGSTTGWRAREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQATQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLKALDTRMAAESRRVLLLAGRLAAQSLDTSGLRHVQLAFFPPGTVHPLERGVVQQVKGHYRQAMLLKAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHILHLEHDLVHVTRKNHARQAGVRGLGHQS
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for CENPB recombinant protein
This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65,171 Da
NCBI Official Full Name
major centromere autoantigen B
NCBI Official Synonym Full Names
centromere protein B
NCBI Official Symbol
CENPB
NCBI Protein Information
major centromere autoantigen B
UniProt Protein Name
Major centromere autoantigen B
UniProt Gene Name
CENPB
UniProt Synonym Gene Names
CENP-B
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Product Notes
The CENPB cenpb (Catalog #AAA114088) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-599aa; Full Length of Mature Protein. The amino acid sequence is listed below: GPKRRQLTFR EKSRIIQEVE ENPDLRKGEI ARRFNIPPST LSTILKNKRA ILASERKYGV ASTCRKTNKL SPYDKLEGLL IAWFQQIRAA GLPVKGIILK EKALRIAEEL GMDDFTASNG WLDRFRRRHG VVSCSGVARA RARNAAPRTP AAPASPAAVP SEGSGGSTTG WRAREEQPPS VAEGYASQDV FSATETSLWY DFLPDQAAGL CGGDGRPRQA TQRLSVLLCA NADGSEKLPP LVAGKSAKPR AGQAGLPCDY TANSKGGVTT QALAKYLKAL DTRMAAESRR VLLLAGRLAA QSLDTSGLRH VQLAFFPPGT VHPLERGVVQ QVKGHYRQAM LLKAMAALEG QDPSGLQLGL TEALHFVAAA WQAVEPSDIA ACFREAGFGG GPNATITTSL KSEGEEEEEE EEEEEEEEGE GEEEEEEGEE EEEEGGEGEE LGEEEEVEEE GDVDSDEEEE EDEESSSEGL EAEDWAQGVV EAGGSFGAYG AQEEAQCPTL HFLEGGEDSD SDSEEEDDEE EDDEDEDDDD DEEDGDEVPV PSFGEAMAYF AMVKRYLTSF PIDDRVQSHI LHLEHDLVHV TRKNHARQAG VRGLGHQS. It is sometimes possible for the material contained within the vial of "Major centromere autoantigen B (CENPB), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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