Enterokinase Active Protein | TMPRSS15 active protein

Human Enterokinase

Cat. Num. AAA79292

• Gene Names: TMPRSS15; ENTK; PRSS7
• Purity: >90% by SDS-PAGE & HPLC analyses
• Synonyms: Enterokinase; N/A; Human Enterokinase; Enteropeptidase; Serine protease 7; TMPRSS15 active protein

• Host: CHO Cells
• Purity/Purification: >90% by SDS-PAGE & HPLC analyses
• Form/Format: Lyophilized from 10mM Sodium Phosphate, pH 7.5 + 1mM Calcium Chloride.
• Sequence: Heavy chain:LTIKESQRGA ALGQSHEARA TFKITSGVTY NPNLQ DKLSV DFKVLAFDLQ QMIDEIFLSS NLKNEYKNSR VLQFENGSII VVFDLFFAQW VSDQNVKEEL IQGLEANKSS QLVTFHIDLN SVDILD KLTT TSHLATPGNV SIECLPGSSP CTDALTCIKA DLFCDGEVNC P DGSDEDNKM CATVCDGRFL LTGSSGSFQA THYPKPSETS VVCQWII RVN QGLSIKLSFD DFNTYYTDIL DIYEGVGSSK ILRASIWETN PG TIRIFSNQ VTATFLIESD ESDYVGFNAT YTAFNSSELN NYEKINCN FE DGFCFWVQDL NDDNEWERIQ GSTFSPFTGP NFDHTFGNAS GFY ISTPTGP GGRQERVGLL SLPLDPTLEP ACLSFWYHMY GENVHKLSI N ISNDQNMEKT VFQKEGNYGD NWNYGQVTLN ETVKFKVAFN AFKN KILSDI ALDDISLTYG ICNGSLYPEP TLVPTPPPEL PTDCGGPFEL WEPNTTFSST NFPNSYPNLA FCVWILNAQK GKNIQLHFQE FDLEN INDVV EIRDGEEADS LLLAVYTGPG PVKDVFSTTN RMTVLLITND VLARGGFKAN FTTGYHLGIPEPCKADHFQC KNGECVPLVN LCDGHLH CED GSDEADCVRF FNGTTNNNGL VRFRIQSIWH TACAENWTTQ IS NDVCQLLG LGSGNSSKPI FSTDGGPFVK LNTAPDGHLI LTPSQQCL QD SLIRLQCNHK SCGKKLAAQD ITPK; Light Chain:IVG GSNAKEG AWPWVVGLYY GGRLLCGASL VSSDWLVSAA HCVYGRNLE P SKWTAILGLH MKSNLTSPQT VPRLIDEIVI NPHYNRRRKD NDIA MMHLEF KVNYTDYIQP ICLPEENQVF PPGRNCSIAG WGTVVYQGTT ANILQEADVP LLSNERCQQQ MPEYNITENM ICAGYEEGGI DSCQG DSGGP LMCQENNRWF LAGVTSFGYK CALPNRPGVY ARVSRFTEWI QSFLH
• Sequence Length: 235

• Endotoxin Level: < 0.2 ng / ug of protein (<2EU/ug).
• Biological Activity: Sequentially cleaves carboxyl side of D-D-D-D-K.
• Reconstitution: Centrifuge vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
• Preparation and Storage: The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.

Related Product Information for TMPRSS15 active protein

Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Enterokinase sequentially cleaves carboxyl side of D-D-D-D-K. Human Enterokinase is expressed as a linear 1019 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of Enterokinase, which consists of two polypeptide chains (heavy chain and light chain) held together by a single disulfide bond, resulting in formation of a biologically active heterodimer. The heavy chain consists of 784 amino acid residues, and the light consists of 235 amino acid residues.

Product Categories/Family for TMPRSS15 active protein

Cytokines & Growth Factors

NCBI and Uniprot Product Information

• NCBI GI #: 223942069
• NCBI GeneID: 5651
• NCBI Accession #: NP_002763.2
• NCBI GenBank Nucleotide #: NM_002772.2
• UniProt Accession #: P98073; Q2NKL7
• Molecular Weight: 108.7 kDa
• NCBI Official Full Name: enteropeptidase
• NCBI Official Synonym Full Names: transmembrane protease, serine 15
• NCBI Official Symbol: TMPRSS15
• NCBI Official Synonym Symbols: ENTK; PRSS7
• NCBI Protein Information: enteropeptidase; serine protease 7; enterokinase catalytic subunit; protease, serine, 7 (enterokinase)
• UniProt Protein Name: Enteropeptidase
• UniProt Gene Name: TMPRSS15
• UniProt Synonym Gene Names: ENTK; PRSS7
• UniProt Entry Name: ENTK_HUMAN