Host
HEK293 cells
Purity/Purification
>95%. Affinity purification
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization.
Sequence
CB1 (Met1-Gln116) + (Asp176-Asn187) + (Asn256-Glu273) + (Asp1366-Thr377) + hFc (Glu99-Ala330)
Origin
Human
Reconstitution
Reconstitute with deionized water
Tag
C-Human Fc tag
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Related Product Information for CB1 recombinant protein
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,858 Da
NCBI Official Full Name
cannabinoid receptor 1 isoform a
NCBI Official Synonym Full Names
cannabinoid receptor 1 (brain)
NCBI Official Symbol
CNR1
NCBI Official Synonym Symbols
CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5
NCBI Protein Information
cannabinoid receptor 1; central cannabinoid receptor
UniProt Protein Name
Cannabinoid receptor 1
UniProt Gene Name
CNR1
UniProt Synonym Gene Names
CNR; CB-R; CB1
UniProt Entry Name
CNR1_HUMAN
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Product Notes
The CB1 cnr1 (Catalog #AAA47331) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: CB1 (Met1-Gln1 16) + (Asp176-As n187) + (Asn256-Gl u273) + (Asp1366-T hr377) + hFc (Glu99-Ala 330). It is sometimes possible for the material contained within the vial of "CB1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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