Endostatin Recombinant Protein | COL18A1 recombinant protein
Endostatin protein
Gene Names
COL18A1; KS; KNO; KNO1
Purity
> 98% pure by SDS-PAGE
Synonyms
Endostatin; N/A; Endostatin protein; COL18A1 recombinant protein
Host
E. Coli
Purity/Purification
> 98% pure by SDS-PAGE
Form/Format
Supplied lyophilized from 10mM sodium phosphate, pH 7.5. 0.2 micron sterile filtered.
Concentration
100ug per vial; lyophilized (varies by lot)
Sequence Length
102
Species
Human
Grade
Recombinant
Contaminants
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Reconstitution
Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Residues
Region of Endostatin protein corresponding to amino acids MHSHRDFQPV LHLVALNSPL SGGMRGIRGA DFQCFQQARA VGLAGTFRAF LSSRLQDLYS IVRRADRAAV PIVNLKDELL FPSWEALFSG SEGPLKPGAR IFSFDGKDVL RHPTWPQKSV WHGSDPNGRR LTESYCETWR TEAPSATGQA SSLLGGRLLG QSAASCHHAY IVLCIENSFM TASK.
Biohazard
Use standard laboratory precautions when handling this material.
Biological Significance
Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF basic.
Preparation and Storage
Ships on blue ice. Upon receipt store at-20 degree. once reconstituted, store at 4°C short term. For longer storage after reconstiution, further dilute in a buffer containing a carrier protein and store -20°C to -80°C.
Related Product Information for COL18A1 recombinant protein
Purified recombinant Human Endostatin protein
Product Categories/Family for COL18A1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
endostatin variant, partial
NCBI Official Synonym Full Names
collagen, type XVIII, alpha 1
NCBI Official Symbol
COL18A1
NCBI Official Synonym Symbols
KS; KNO; KNO1
NCBI Protein Information
collagen alpha-1(XVIII) chain
UniProt Protein Name
Collagen alpha-1(XVIII) chain
UniProt Gene Name
COL18A1
UniProt Entry Name
COIA1_HUMAN
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Product Notes
The COL18A1 col18a1 (Catalog #AAA14388) is a Recombinant Protein produced from E. Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Endostatin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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