SDS-PAGE
COVID 19 NSP8 Coronavirus Recombinant Protein | COVID-19 recombinant protein
Recombinant SARS-CoV-2 (2019-nCoV) NSP8
Applications
Immunogen
Purity
>90% as determined by SDS-PAGE
Synonyms
COVID 19 NSP8 Coronavirus; N/A; Recombinant SARS-CoV-2 (2019-nCoV) NSP8; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; NSP8, SARS-CoV-2 NSP8; COVID-19 recombinant protein
Host
E Coli
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Supplied as a solution form in PBS, pH 7.5 or as lyophilized from PBS, pH 7.5
Sequence Length
198
Applicable Applications for COVID-19 recombinant protein
Immunogen
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Reconstitution
It is suggested to reconstitute the recombinant protein with ddH2O to the concentration of 1mg/ml.
Preparation and Storage
Store at -20 to -80°C for twelve months from the date of receipt.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
SDS-PAGE
SDS-PAGE
Related Product Information for COVID-19 recombinant protein
Recombinant SARS-CoV-2 NSP8 is produced by E.coli expression system and the target gene encoding Ala1-Gln198 is expressed with N-His Tag
Background
Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.
Background
Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Actual Molecular Mass: 24kDa
Predicted Molecular Mass: 24.18kDa
Predicted Molecular Mass: 24.18kDa
NCBI Official Full Name
nsp8
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Product Notes
The COVID-19 (Catalog #AAA41019) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's COVID 19 NSP8 Coronavirus can be used in a range of immunoassay formats including, but not limited to, Immunogen. Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 NSP8 Coronavirus, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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