Cytochrome P450 2A6 (CYP2A6) Recombinant Protein | CYP2A6 recombinant protein
Recombinant Human Cytochrome P450 2A6 (CYP2A6), partial
Gene Names
CYP2A6; CPA6; CYP2A; CYP2A3; P450PB; CYPIIA6; P450C2A
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Cytochrome P450 2A6 (CYP2A6); N/A; Recombinant Human Cytochrome P450 2A6 (CYP2A6), partial; CYP2A6 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
29-494aa; Partial
Sequence
SKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for CYP2A6 recombinant protein
This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60.8 kDa
NCBI Official Full Name
cytochrome P450 2A6
NCBI Official Synonym Full Names
cytochrome P450 family 2 subfamily A member 6
NCBI Official Symbol
CYP2A6
NCBI Official Synonym Symbols
CPA6; CYP2A; CYP2A3; P450PB; CYPIIA6; P450C2A
NCBI Protein Information
cytochrome P450 2A6
UniProt Protein Name
Cytochrome P450 2A6
UniProt Gene Name
CYP2A6
UniProt Synonym Gene Names
CYP2A3
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Product Notes
The CYP2A6 cyp2a6 (Catalog #AAA113436) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 29-494aa; Partial. The amino acid sequence is listed below: SKGKLPPGPT PLPFIGNYLQ LNTEQMYNSL MKISERYGPV FTIHLGPRRV VVLCGHDAVR EALVDQAEEF SGRGEQATFD WVFKGYGVVF SNGERAKQLR RFSIATLRDF GVGKRGIEER IQEEAGFLID ALRGTGGANI DPTFFLSRTV SNVISSIVFG DRFDYKDKEF LSLLRMMLGI FQFTSTSTGQ LYEMFSSVMK HLPGPQQQAF QLLQGLEDFI AKKVEHNQRT LDPNSPRDFI DSFLIRMQEE EKNPNTEFYL KNLVMTTLNL FIGGTETVST TLRYGFLLLM KHPEVEAKVH EEIDRVIGKN RQPKFEDRAK MPYMEAVIHE IQRFGDVIPM SLARRVKKDT KFRDFFLPKG TEVYPMLGSV LRDPSFFSNP QDFNPQHFLN EKGQFKKSDA FVPFSIGKRN CFGEGLARME LFLFFTTVMQ NFRLKSSQSP KDIDVSPKHV GFATIPRNYT MSFLPR. It is sometimes possible for the material contained within the vial of "Cytochrome P450 2A6 (CYP2A6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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