Host
E Coli
Purity/Purification
>=80% (SDS-PAGE)
Form/Format
Liquid. In 50mM HEPES, pH7.4, containing 100mM sodium chloride, 0.5% CHAPS, 1mM EDTA, 10% glycerol and 10mM DTT
Concentration
100U/ul (varies by lot)
Specific Activity
One unit=1 pmol/min at 30 degree C using Ac-VEID-pNA (200mM) as substrate
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
For long term storage, store at -80°C
Avoid freeze/thaw cycles
Shipping: Shipped on Dry Ice
After initial defrost, aliquot product into individual tubes and refreeze the remaining, unused enzyme quickly by snap-freezing in a dry/ice ethanol bath or liquid nitrogen, if possible
Avoid freeze/thaw cycles
Shipping: Shipped on Dry Ice
After initial defrost, aliquot product into individual tubes and refreeze the remaining, unused enzyme quickly by snap-freezing in a dry/ice ethanol bath or liquid nitrogen, if possible
Related Product Information for CASP6 active protein
Effector caspase responsible for the cleavage of nuclear lamins in apoptosis. Caspase-6 cleavages of various other protein targets have been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease (b-amyloid precursor protein), Huntington's disease (huntingtin).
Product Categories/Family for CASP6 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18 + 11 kDa subunits
NCBI Official Full Name
caspase-6 isoform alpha preproprotein
NCBI Official Synonym Full Names
caspase 6, apoptosis-related cysteine peptidase
NCBI Official Symbol
CASP6
NCBI Official Synonym Symbols
MCH2
NCBI Protein Information
caspase-6; apoptotic protease MCH-2; caspase 6, apoptosis-related cysteine protease
UniProt Protein Name
Caspase-6
UniProt Gene Name
CASP6
UniProt Synonym Gene Names
MCH2; CASP-6
UniProt Entry Name
CASP6_HUMAN
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Product Notes
The CASP6 casp6 (Catalog #AAA77044) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Caspase-6, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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