Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF) Active Protein | CSF2 active protein
Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF)
Gene Names
CSF2; GMCSF; MGC131935; MGC138897
Purity
>98% as determined by RPHPLC and SDS-PAGE.
Synonyms
Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF); N/A; Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF); CSF2 active protein
Host
E Coli
Specificity
Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF)
Purity/Purification
>98% as determined by RPHPLC and SDS-PAGE.
Form/Format
Sterile filtered and lyophilized after dialysis against 2mM sodium phosphate, pH 7.4. Purified by proprietary chromatographic techniques.
Sequence
AMINO ACID SEQUENCE
The first five N-terminal amino acids are Ala-Pro-Ala-Arg-Ser. N-terminal methionine is removed enzymatically.
The first five N-terminal amino acids are Ala-Pro-Ala-Arg-Ser. N-terminal methionine is removed enzymatically.
Biological Activity
E050 by dose-dependent stimulation of proliferation of human TF-1 cells (human erythroleukemic indicator cell line) is <0.1ng/ml which corresponds to a Specific Activity of 11,100,000 IU/mg.
Preparation and Storage
Reconstitute lyophilized GM-CSF in sterile distilled H20 at not less than 100ug/ml. This can be further diluted in other aqueous solutions. Store lyophilized product desiccated below -18 degree C. After reconstitution, GMCSF may be stored at 4 degree C for 2-7 days and below -18 degree C for future use. For long term storage, addition of 0.1 % human serum albumin or bovine serum albumin is recommended. Avoid multiple freeze-thaw cycles.
Related Product Information for CSF2 active protein
Describtion: Recombinant human GM-CSF produced in E. coli is a single, non-glycosylated polypeptide containing 127 amino acids with a molecular weight of 14,4770a.
Background: GM-CSF was first identified as a growth factor that supports in vitro colony formation of granulocyte-macrophage progenitor cells. It is produced in response to immune or inflammatory stimuli by activated T cells, B cells, macrophages, mast cells, fibroblasts, and alveolar epithelial cells. GM-CSF is a 22kOa protein, 144 amino acids, composed of four bundle alpha helices.
Background: GM-CSF was first identified as a growth factor that supports in vitro colony formation of granulocyte-macrophage progenitor cells. It is produced in response to immune or inflammatory stimuli by activated T cells, B cells, macrophages, mast cells, fibroblasts, and alveolar epithelial cells. GM-CSF is a 22kOa protein, 144 amino acids, composed of four bundle alpha helices.
Product Categories/Family for CSF2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,295 Da
NCBI Official Full Name
granulocyte-macrophage colony-stimulating factor
NCBI Official Synonym Full Names
colony stimulating factor 2 (granulocyte-macrophage)
NCBI Official Symbol
CSF2
NCBI Official Synonym Symbols
GMCSF; MGC131935; MGC138897
NCBI Protein Information
granulocyte-macrophage colony-stimulating factor; CSF; molgramostin; sargramostim; OTTHUMP00000065962; granulocyte-macrophage colony stimulating factor
UniProt Protein Name
Granulocyte-macrophage colony-stimulating factor
UniProt Gene Name
CSF2
UniProt Synonym Gene Names
GMCSF
UniProt Entry Name
CSF2_HUMAN
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Product Notes
The CSF2 csf2 (Catalog #AAA47951) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: AMINO ACID SEQUENCEThe first five N-terminal amino acids are Ala-Pro-Al a-Arg-Ser. N-terminal methionine is removed enzymatica lly. It is sometimes possible for the material contained within the vial of "Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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