IL-21 active protein
Recombinant Animal Free Human IL-21 Protein
Gene Names
IL21; Za11; IL-21; CVID11
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
IL-21; N/A; Recombinant Animal Free Human IL-21 Protein; Interleukin-21; IL-21 active protein
Host
E coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid in. Phosphate-Buffered Saline (pH7.4)
Concentration
0.25mg/ml (determined by absorbance at 280nm) (varies by lot)
Sequence Positions
30-162aa
Sequence
MQGQDRHMIR MRQLIDIVDQ LKNYVNDLVP EFLPAPEDVE TNCEWSAFSC FQKAQLKSAN GNNERIINV SIKKLKRKPP STNAGRRQKH RLTCPSCDSY EKKPPKEFLE RFKSLLQKMI HQHLSSRTHG SEDS
Applicable Applications for IL-21 active protein
Bioactivity, SDS-PAGE
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Related Product Information for IL-21 active protein
IL-21, also known as Interleukin-21, is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumor responses. It has broad immunoregulatory activity and can modulate both humoral and cell-mediated responses. It is important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. It is produced by activated T cell, and it influences proliferation of T and B cells and cytolytic activity of natural killer cells. It may be a critical factor in the control of persistent viral infections. It has a potential predicating significance for survival Time in patients in the development of sporadic CRC. It binds to the IL-21R and can activate janus kinase JAK1, JAK3, STAT1, and STAT3 in EDgamma-16 cells. Recombinant human IL-21, was expressed in E coli and purified by using conventional chromatography techniques. Produced using non-animal reagents in an animal-free laboratory
Product Categories/Family for IL-21 active protein
References
Gui G., et al. (2017) Clin Immunol. 183:266-272.
Parrish-Novak J., et al. (2000) Nature. 408(6808):57-63.
Parrish-Novak J., et al. (2000) Nature. 408(6808):57-63.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18 kDa
NCBI Official Full Name
interleukin-21 isoform 1
NCBI Official Synonym Full Names
interleukin 21
NCBI Official Symbol
IL21
NCBI Official Synonym Symbols
Za11; IL-21; CVID11
NCBI Protein Information
interleukin-21; interleukin-21 isoform
UniProt Protein Name
Interleukin-21
UniProt Gene Name
IL21
UniProt Synonym Gene Names
IL-21
UniProt Entry Name
IL21_HUMAN
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Product Notes
The IL-21 il21 (Catalog #AAA48978) is an Active Protein produced from E coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 30-162aa. AAA Biotech's IL-21 can be used in a range of immunoassay formats including, but not limited to, Bioactivity, SDS-PAGE. Researchers should empirically determine the suitability of the IL-21 il21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MQGQDRHMIR MRQLIDIVDQ LKNYVNDLVP EFLPAPEDVE TNCEWSAFSC FQKAQLKSAN GNNERIINV SIKKLKRKPP STNAGRRQKH RLTCPSCDSY EKKPPKEFLE RFKSLLQKMI HQHLSSRTHG SEDS. It is sometimes possible for the material contained within the vial of "IL-21, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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