Application Data
MCP-4 (CCL13) Active Protein | MCP-4 active protein
Recombinant Human MCP-4 (CCL13)
Gene Names
CCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13
Purity
>95% as determined by SDS-PAGE
Synonyms
MCP-4 (CCL13); N/A; Recombinant Human MCP-4 (CCL13); Monocyte chemotactic protein 4; CCL13; NCC-1; C-C motif chemokine 13; Small-inducible cytokine A13; MCP4; NCC1; SCYA13; Recombinant Human Monocyte Chemoattractant Protein-4 (CCL13); MCP-4 active protein
Host
E Coli
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from a 0.2 um filtered solution in PB, 100mM NaCl, pH 7.5
Sequence Length
98
Bioactivity
Determined by its ability to chemoattract human monocytes using a concentration range of 20-40 ng/mL.
Endotoxin Level
<1.0 EU/ug of recombinant protein as determined by the LAL method.
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Preparation and Storage
The lyophilized protein is stable for at least one year from date of receipt at-70 degree C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8 degree C for one month, or at-20 degree C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Application Data
Application Data
Application Data
Application Data
Related Product Information for MCP-4 active protein
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is member of a distinct, structurally-related subclass of CC chemokines. MCP-4/CCL13 is a major chemoattractants for eosinophils, basophils, monocytes, and T lymphocytes. The MCP protein family bind to specific G-protein-coupled receptors, initiating a signal cascade within the cell. Expression of MCP-4/CCL13 mRNA and protein is greater in the sputum, epithelium, submucosal inflammatory cells, and bronchoalveolar lavage fluid of asthmatics than in healthy individuals. Involvement of MCPs has also been demonstrated in renal inflammation and atopic dermatitis. The expression of this protein is also correlated with enhanced inflammatory immune responses during immunotherapy. The recombinant construct corresponds to the "short-chain" of CCL13 spanning amino acids 24-98.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
9.0 kDa
NCBI Official Full Name
C-C motif chemokine 13
NCBI Official Synonym Full Names
C-C motif chemokine ligand 13
NCBI Official Symbol
CCL13
NCBI Official Synonym Symbols
NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13
NCBI Protein Information
C-C motif chemokine 13
UniProt Protein Name
C-C motif chemokine 13
UniProt Gene Name
CCL13
UniProt Synonym Gene Names
MCP4; NCC1; SCYA13; MCP-4
UniProt Entry Name
CCL13_HUMAN
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Product Notes
The MCP-4 ccl13 (Catalog #AAA214244) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MCP-4 (CCL13), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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