Application Data
PlGF active protein
Recombinant Human PlGF
Gene Names
PGF; PGFL; PIGF; PLGF; PlGF-2; D12S1900; SHGC-10760
Purity
>95% as determined by SDS-PAGE
Synonyms
PlGF; N/A; Recombinant Human PlGF; PGF; PGLF; PlGF active protein
Host
E Coli
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from a 0.2 um filtered solution in Citrate, phosphate and NaCl (pH 4.0)
Sequence Length
149
Bioactivity
The ED50 was found to be <0.2ng/ml using dose dependent proliferation of trophoblast cells.
Endotoxin Level
<1.0 EU/ug of recombinant protein as determined by the LAL method
Reconstitution
A quick spin of the vial followed by reconstitution in PBS to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Preparation and Storage
The lyophilized protein is stable for at least one year from date of receipt at-70 degree C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8 degree C for one month, or at-20 degree C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Application Data
Application Data
Application Data
Application Data
Related Product Information for PlGF active protein
Human PlGF, or Placental Growth Factor, is part of the PDGF/VEGF family and contains the 8 cysteine residues conserved in the family. It can be alternately spliced into three different mature forms. PGF is typically found as a disulfide linked dimer which is highly glycosylated. It is a key molecule involved in vasculogenesis and angiogenesis, especially during embryogenesis. It also induces the activation of monocytes, as well as their migration and production of inflammatory cytokines. It is primarily expressed by the placental trophoblast during pregnancy, but is also expressed in villious trophoblasts, decidual cells, erythroblasts, keratinocytes, and somewhat in endothelial cells. PGF signals by binding VEGF R1, and competes with VEGF for binding. Recombinant PlGF is a 15.0 kDa protein.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15.0 kDa
NCBI Official Full Name
placenta growth factor isoform 2
NCBI Official Synonym Full Names
placental growth factor
NCBI Official Symbol
PGF
NCBI Official Synonym Symbols
PGFL; PIGF; PLGF; PlGF-2; D12S1900; SHGC-10760
NCBI Protein Information
placenta growth factor
UniProt Protein Name
Placenta growth factor
UniProt Gene Name
PGF
UniProt Synonym Gene Names
PGFL; PLGF; PlGF
UniProt Entry Name
PLGF_HUMAN
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Product Notes
The PlGF pgf (Catalog #AAA214308) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PlGF, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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