Thymic Stromal Lymphopoietin/TSLP Active Protein | TSLP active protein

Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His)

Cat. Num. AAA177974

• Purity: >95% as determined by reducing SDS-PAGE
• Synonyms: Thymic Stromal Lymphopoietin/TSLP; N/A; Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His); Thymic stromal lymphopoietin; Thymic stroma-derived lymphopoietin; TSLP ; TSLP active protein

• Host: E Coli
• Purity/Purification: >95% as determined by reducing SDS-PAGE
• Form/Format: Lyophilized from a 0.2um filtered solution of 20mM PB, 500mM NaCl, pH7.4.
• Sequence: Tyr29-Gln159(Glu37Gln)

• Species: Cynomolgus
• Tag: C-6His
• Endotoxin: <1.0EU per ug as determined by the LAL method.
• Protein Construction: Recombinant Cynomolgus Thymic Stromal Lymphopoietin is produced by our E Coli expression system and the target gene encoding Tyr29-Gln159(Glu37Gln) is expressed with a 6His tag at the C-terminus.
• Activity: Immobilized Mouse TSLPR-Fc at 10ug/ml (100ul/well) can bind Biotinylated Cynomolgus TSLP-His . The ED50 of Cynomolgus TSLP-His is 3.2ug/ml.
• Preparation and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.; This product is provided as lyophilized powder which is shipped with ice packs.

Bioactivity

SDS-PAGE

Related Product Information for TSLP active protein

Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.

NCBI and Uniprot Product Information

• Molecular Weight: Mol. Mass: 16.2kDa; AP Mol. Mass: 16kDa