BMP-13 (GDF6) active protein
Human BMP-13 (GDF6)
Gene Names
Gdf6; BMP13; GDF16
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analysis
Synonyms
BMP-13 (GDF6); N/A; Human BMP-13 (GDF6); GDF6; KFM; KFS; KFS1; KFSL; SGM1; BMP13; CDMP2; MCOP4; SCDO4; MCOPCB6; BMP-13 (GDF6) active protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 95% by SDS-PAGE & HPLC analysis
Form/Format
Lyophilized
Sequence
TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAY HCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL T PISILYIDA GNNVVYKQYE DMVVESCGCR
Sequence Length
454
Endotoxin level
< 0.1 ng /ug of protein (<1EU/ug)
Structural Information
disulphide-linked homodimer
Length (aa)
120
Biological Activity
The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 ug/ml.
Reconstitution
Centrifuge vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
Avoid repeated freeze and thaw cycles.
Avoid repeated freeze and thaw cycles.
Related Product Information for BMP-13 (GDF6) active protein
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.
Product Categories/Family for BMP-13 (GDF6) active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27.0 kDa
NCBI Official Full Name
growth/differentiation factor 6
NCBI Official Synonym Full Names
growth differentiation factor 6
NCBI Official Symbol
Gdf6
NCBI Official Synonym Symbols
BMP13; GDF16
NCBI Protein Information
growth/differentiation factor 6; GDF-6; growth differentiation factor 16; growth/differentiation factor 16
UniProt Protein Name
Growth/differentiation factor 6
UniProt Gene Name
Gdf6
UniProt Synonym Gene Names
Gdf-6; Gdf16; GDF-6
UniProt Entry Name
GDF6_MOUSE
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Product Notes
The BMP-13 (GDF6) gdf6 (Catalog #AAA79222) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human BMP-13 (GDF6) reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAY HCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL T PISILYIDA GNNVVYKQYE DMVVESCGCR. It is sometimes possible for the material contained within the vial of "BMP-13 (GDF6), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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