Application Data
BMP-2 active protein
Human BMP-2
Gene Names
BMP2; BDA2; BMP2A
Reactivity
Human
Purity
> 95% by SDS-PAGE & silver stain
Synonyms
BMP-2; N/A; Human BMP-2; Recombinant Human Bone Morphogenetic Protein-2; BMP-2A; Bone morphogenetic protein 2A; BMP-2 active protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 95% by SDS-PAGE & silver stain
Form/Format
Lyophilized
Sequence
MQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPF PLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVV LKNYQDMVVEGCGCR
Sequence Length
115
Endotoxin Level
< 0.1ng per ug of BMP-2
Biological Activity
Measured by the ability of BMP-2 to induce alkaline phosphatase production by C2C12 myogenic cells. The ED50 for this effect is typically 0.3-0.8 ug/ml.
Reconstitution
The lyophilized BMP-2 is best soluble in 50 mM acetic acid at a concentration of 0.1mg/ml but should be also soluble in most aqueous buffers when the pH is below 6.0.
Preparation and Storage
Lyophilized samples are stable for greater than six months at -20 degree C to -70 degree C. Reconstituted BMP-2 should be stored in working aliquots at -20 degree C. Avoid repeated freeze-thaw cycles!
Application Data
Application Data
Application Data
Application Data
Related Product Information for BMP-2 active protein
Human Bone Morphogenetic Protein-2 (BMP-2) is a disulfide-bonded homodimeric protein with an apparent molecular weight of 26 kDa. BMP-2 regulates similarly to its nearest homologue BMP-4 diverse fundamental processes during embryonic development: BMP-2 and other BMP proteins have great potential for medical therapeutic applications, in particular because they allow or at least accelerate the ossification of extensive bone lesions. The amino acid sequence of recombinant human BMP-2 starts with MQAKHKQ (position 283) containing the Met from the E. coli expression vector. BMP-2 is a heparin binding protein.
Product Categories/Family for BMP-2 active protein
References
1. Wozney et al., Science 242:1528, 1988 2. Ruppert et al., Eur J Biochem 237:295, 1996
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26.0 kDa
NCBI Official Full Name
bone morphogenetic protein 2 preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 2
NCBI Official Symbol
BMP2
NCBI Official Synonym Symbols
BDA2; BMP2A
NCBI Protein Information
bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A
UniProt Protein Name
Bone morphogenetic protein 2
UniProt Gene Name
BMP2
UniProt Synonym Gene Names
BMP2A; BMP-2; BMP-2A
UniProt Entry Name
BMP2_HUMAN
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Product Notes
The BMP-2 bmp2 (Catalog #AAA79170) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human BMP-2 reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR. It is sometimes possible for the material contained within the vial of "BMP-2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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