Epstein-Barr Virus EBNA1 Recombinant Protein | EBV EBNA1 recombinant protein
Epstein-Barr Virus EBNA1 Recombinant
Applications
Western Blot, ELISA
Purity
>90%
Synonyms
Epstein-Barr Virus EBNA1; N/A; Epstein-Barr Virus EBNA1 Recombinant; ebna1; ebna-1; ebv; epstein barr; EBV EBNA1 recombinant protein
Host
N/A (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders)
Purity/Purification
>90%
Form/Format
0.2 um filtered 50mM Tris-HCI pH 8, 10mM glutathione, 60mM NaCI, 0.25% Sarkosyl and 50% Glycerol.
Concentration
Bradford test: 7.14 mg/mL (varies by lot)
Sequence Length
641
Applicable Applications for EBV EBNA1 recombinant protein
WB (Western Blot), ELISA
Host Note
DNA sequence encoding fragment of EBV EBNA1 was expressed in Escherichia Coli.
Preparation and Storage
This protein can be stored in working aliquots at 2-8°C for one month, or at -20°C for six months without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
Avoid repeated freeze/thaw cycles.
Related Product Information for EBV EBNA1 recombinant protein
EBNA1 is the only EBV protein consistently expressed in all proliferating infected cells and plays several important roles in EBV latent infection, including the initiation of EBV DNA replication, the mitotic segregation of the EBV genomes, and transcriptional activation of other EBV latency proteins. several pieces of evidence suggest that EBNA1 plays a direct role in cellular transformation by EBV. First, EBNA1 is expressed in all EBV-associated tumors and is the only viral protein expressed in some of these tumors. Second, transgenic mice expressing EBNA1 develop malignant B cell lymphomas. Third, the expression of EBNA1 in Hodgkin cells enhances their ability to form tumors in nonobese diabetic-SCID mice. Fourth, EBV genomes lacking the EBNA1 gene are several thousand-fold less efficient at B cell immortalization than EBV genomes expressing EBNA1. Fifth, interference with EBNA1 function in Burkitt's lymphoma cells by overexpression of the EBNA1 DNA binding domain increased cell death, suggesting that EBNA1 normally provides a survival function for these cells.
Product Categories/Family for EBV EBNA1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Tested on SDS-PAGE: 45 kDa
NCBI Official Full Name
EBNA-1
UniProt Protein Name
Epstein-Barr nuclear antigen 1
UniProt Gene Name
EBNA1
UniProt Synonym Gene Names
EBNA-1
UniProt Entry Name
EBNA1_EBVB9
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Product Notes
The EBV EBNA1 ebna1 (Catalog #AAA76094) is a Recombinant Protein produced from N/A (Host protein expression may be lot-specific and can be subject to change during production, including bulk orders) and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Epstein-Barr Virus EBNA1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the EBV EBNA1 ebna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Epstein-Barr Virus EBNA1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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