Application Data
(The purity of KAT9 (ELP3) was determined to be >70% by densitometry. Approx. MW 86kDa.)
KAT9 (ELP3) recombinant protein
KAT9 (ELP3) recombinant protein
Gene Names
ELP3; KAT9
Purity
>70%
Synonyms
KAT9 (ELP3); N/A; KAT9 (ELP3) recombinant protein; KAT9; ELP3; FLJ10422
Purity/Purification
>70%
Form/Format
Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Concentration
0.1ug/ul (varies by lot)
Sequence Length
3232
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Ships on Dry Ice.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Application Data
(The purity of KAT9 (ELP3) was determined to be >70% by densitometry. Approx. MW 86kDa.)
Application Data
(The purity of KAT9 (ELP3) was determined to be >70% by densitometry. Approx. MW 86kDa.)
Related Product Information for KAT9 (ELP3) recombinant protein
Recombinant full-length human KAT9 (ELP3) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_018091.
KAT9 (also known as ELP3) is the catalytic subunit of the histone acetyltransferase (HAT) elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons. The knockdown of KAT9 by antisense morpholinos in zebrafish embryos resulted in dose-dependent shortening and abnormal branching of motor neurons with no concomitant morphologic abnormalities (1). KAT9 knockdown also impairs paternal DNA demethylation as indicated by reporter binding, immunostaining, and bisulfite sequencing (2).
KAT9 (also known as ELP3) is the catalytic subunit of the histone acetyltransferase (HAT) elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons. The knockdown of KAT9 by antisense morpholinos in zebrafish embryos resulted in dose-dependent shortening and abnormal branching of motor neurons with no concomitant morphologic abnormalities (1). KAT9 knockdown also impairs paternal DNA demethylation as indicated by reporter binding, immunostaining, and bisulfite sequencing (2).
Product Categories/Family for KAT9 (ELP3) recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens elongator acetyltransferase complex subunit 3 (ELP3), transcript variant 1, mRNA
NCBI Official Synonym Full Names
elongator acetyltransferase complex subunit 3
NCBI Official Symbol
ELP3
NCBI Official Synonym Symbols
KAT9
NCBI Protein Information
elongator complex protein 3; elongation protein 3 homolog
UniProt Protein Name
Elongator complex protein 3
UniProt Gene Name
ELP3
UniProt Synonym Gene Names
hELP3
UniProt Entry Name
ELP3_HUMAN
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Product Notes
The KAT9 (ELP3) elp3 (Catalog #AAA14242) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "KAT9 (ELP3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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