Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2) Recombinant Protein | ENOX2 recombinant protein
Recombinant Human Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2), Partial
Gene Names
ENOX2; APK1; tNOX; COVA1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2); N/A; Recombinant Human Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2), Partial; APK1 antigen; Cytosolic ovarian carcinoma antigen 1; Tumor-associated hydroquinone oxidase; tNOX; COVA1; ENOX2 recombinant protein
Host
E Coli
Specificity
Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Not found in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells. Found on the cell borders of renal, kidney and ovarian carcinomas but not on the borders of surrounding non-cancerous stromal cells.
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
327-610aa; Partial
Sequence
GILIQFEQIVAVYHSASKQKAWDHFTKAQRKNISVWCKQAEEIRNIHNDELMGIRREEEMEMSDDEIEEMTETKETEESALVSQAEALKEENDSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKKEAELEKLKDDKLQVEKMLENLKEKESCASRLCASNQDSEYPLEKTMNSSPIKSEREALLVGIISTFLHVHPFGASIEYICSYLHRLDNKICTSDVECLMGRLQHTFKQEMTGVGASLEKRWKFCGFEGLKLT
Species
Human
Tag
N-terminal 10xHis-tagged and C-terminal Myc-tagged
Subcellular Location
Cell Membrane, Secreted, Extracellular Space
Protein Families
ENOX family
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for ENOX2 recombinant protein
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.
Product Categories/Family for ENOX2 recombinant protein
References
"Inhibition of plasma membrane NADH oxidase activity and growth of HeLa cells by natural and synthetic retinoids." Dai S., Morre D.J., Geilen C.C., Almond-Roesler B., Orfanos C.E., Morre D.M. Mol. Cell. Biochem. 166:101-109(1997).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40.1 kDa
NCBI Official Full Name
ecto-NOX disulfide-thiol exchanger 2 isoform a
NCBI Official Synonym Full Names
ecto-NOX disulfide-thiol exchanger 2
NCBI Official Symbol
ENOX2
NCBI Official Synonym Symbols
APK1; tNOX; COVA1
NCBI Protein Information
ecto-NOX disulfide-thiol exchanger 2
UniProt Protein Name
Ecto-NOX disulfide-thiol exchanger 2
UniProt Gene Name
ENOX2
UniProt Synonym Gene Names
COVA1; tNOX
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Product Notes
The ENOX2 enox2 (Catalog #AAA235623) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 327-610aa; Partial. The amino acid sequence is listed below: GILIQFEQIV AVYHSASKQK AWDHFTKAQR KNISVWCKQA EEIRNIHNDE LMGIRREEEM EMSDDEIEEM TETKETEESA LVSQAEALKE ENDSLRWQLD AYRNEVELLK QEQGKVHRED DPNKEQQLKL LQQALQGMQQ HLLKVQEEYK KKEAELEKLK DDKLQVEKML ENLKEKESCA SRLCASNQDS EYPLEKTMNS SPIKSEREAL LVGIISTFLH VHPFGASIEY ICSYLHRLDN KICTSDVECL MGRLQHTFKQ EMTGVGASLE KRWKFCGFEG LKLT. It is sometimes possible for the material contained within the vial of "Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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