Application Data
(Recombinant Human Autotaxin/E-NPP2 cleave Bis (p-Nitrophenyl) Phosphate (BPNPP). The specific activity is >15000 pmol/min/ug, as measured under the described conditions.)
Autotaxin/E-NPP2 Recombinant Protein | E-NPP2 recombinant protein
Recombinant Human Autotaxin/E-NPP2 Protein
Purity
>90% by SDS-PAGE.
Synonyms
Autotaxin/E-NPP2; N/A; Recombinant Human Autotaxin/E-NPP2 Protein; ENPP2, ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2; E-NPP2 recombinant protein
Host
HEK293 cells
Purity/Purification
>90% by SDS-PAGE.
Form/Format
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.4.Contact us for customized product form or formulation.
Sequence
DSPWTNISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI
Species
Human
Tag
N-His
Endotoxin
<1 EU/ug of the protein by LAL method.
Bio-Activity
Measured by its ability to cleave Bis (p-Nitrophenyl) Phosphate (BPNPP). The specific activity is >15000 pmol/min/ug, as measured under the described conditions.
Preparation and Storage
Store at -20 degree C. Store the lyophilized protein at -20 degree C to -80 degree C up to 1 year from the date of receipt.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
Application Data
(Recombinant Human Autotaxin/E-NPP2 cleave Bis (p-Nitrophenyl) Phosphate (BPNPP). The specific activity is >15000 pmol/min/ug, as measured under the described conditions.)
Application Data
(Recombinant Human Autotaxin/E-NPP2 cleave Bis (p-Nitrophenyl) Phosphate (BPNPP). The specific activity is >15000 pmol/min/ug, as measured under the described conditions.)
SDS-PAGE
(Recombinant Human Autotaxin/E-NPP2 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 100-120kDa.)
SDS-PAGE
(Recombinant Human Autotaxin/E-NPP2 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 100-120kDa.)
Related Product Information for E-NPP2 recombinant protein
ENPP-2, also known as Autotaxin, belongs to the ectonucleotide pyrophosphatase/phosphodiesterase (NPP) family. Some NPPs hydrolyze phosphates from nucleotides and their derivatives. ENPP-2 shares 40 - 50% identity to ENPP1 & 3, all of which contain a N-terminal intracellular domain, a single transmembrane domain and a large extracellular domain that includes a catalytic domain, two somatomedin-B-like domains, and a C-terminal nuclease-like domain.Evidence shows LPA and sphingosine 1-phosphate to be specific inhibitors of ENPP-2. ENPP-2 was originally found to stimulate tumor cell motility and has since been found to enhance tumor invasion and metastasis and to be up-regulated in several types of carcinomas including breast and lung.
Product Categories/Family for E-NPP2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
UniProt Protein Name
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
UniProt Gene Name
ENPP2
UniProt Synonym Gene Names
ATX; PDNP2; E-NPP 2; LysoPLD
UniProt Entry Name
ENPP2_HUMAN
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Product Notes
The E-NPP2 enpp2 (Catalog #AAA283381) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: DSPWTNISGS CKGRCFELQE AGPPDCRCDN LCKSYTSCCH DFDELCLKTA RGWECTKDRC GEVRNEENAC HCSEDCLARG DCCTNYQVVC KGESHWVDDD CEEIKAAECP AGFVRPPLII FSVDGFRASY MKKGSKVMPN IEKLRSCGTH SPYMRPVYPT KTFPNLYTLA TGLYPESHGI VGNSMYDPVF DATFHLRGRE KFNHRWWGGQ PLWITATKQG VKAGTFFWSV VIPHERRILT ILQWLTLPDH ERPSVYAFYS EQPDFSGHKY GPFGPEMTNP LREIDKIVGQ LMDGLKQLKL HRCVNVIFVG DHGMEDVTCD RTEFLSNYLT NVDDITLVPG TLGRIRSKFS NNAKYDPKAI IANLTCKKPD QHFKPYLKQH LPKRLHYANN RRIEDIHLLV ERRWHVARKP LDVYKKPSGK CFFQGDHGFD NKVNSMQTVF VGYGSTFKYK TKVPPFENIE LYNVMCDLLG LKPAPNNGTH GSLNHLLRTN TFRPTMPEEV TRPNYPGIMY LQSDFDLGCT CDDKVEPKNK LDELNKRLHT KGSTEERHLL YGRPAVLYRT RYDILYHTDF ESGYSEIFLM PLWTSYTVSK QAEVSSVPDH LTSCVRPDVR VSPSFSQNCL AYKNDKQMSY GFLFPPYLSS SPEAKYDAFL VTNMVPMYPA FKRVWNYFQR VLVKKYASER NGVNVISGPI FDYDYDGLHD TEDKIKQYVE GSSIPVPTHY YSIITSCLDF TQPADKCDGP LSVSSFILPH RPDNEESCNS SEDESKWVEE LMKMHTARVR DIEHLTSLDF FRKTSRSYPE ILTLKTYLHT YESEI. It is sometimes possible for the material contained within the vial of "Autotaxin/E-NPP2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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