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product-image-AAA14843_APP.jpg Application Data (Structure of AAA14843RNase A, Pancreatic Ribonuclease, Rib 1; Ribonuclease A Family 1; Ribonuclease Pancreatic; Ribonuclease RNase A Family 1; Ribonuclease RNase A Family 1 Pancreatic; RNAseA; RNase 1; RNASE1; RNS1)

Ribonuclease A, Bovine Pancreas Enzyme | RNASE1 enzyme

Ribonuclease A, Bovine Pancreas (RNase A)

Gene Names
RNASE1; RIB1; RNS1
Synonyms
Ribonuclease A, Bovine Pancreas; N/A; Ribonuclease A, Bovine Pancreas (RNase A); E.C.3.1.27.5; Ribonucleate 3'-pyrimidino-oligonucleotidohydrolase; Ribonuclease 1; RNASE1 enzyme
Ordering
For Research Use Only!
Form/Format
Off-white powder
Source
Bovine pancreas
CAS Number
9001-99-4
Activity
78.4 u/mg
Solubility
Soluble at 10mg/ml in analytical grade water. Colorless, clear, complete.
Unit Definition
One unit will cause the hydrolysis of RNA at that rate where the velocity constant k equals unity (Kunitz units) at 25ºC and pH 5.0.
Nomenclature
E;C.3.1.27.5; Ribonucleate 3-pyrimidino-oligonucleotidohydralase; Ribonuclease 1
Note
Hygroscopic. Keep tightly closed and desiccated
Preparation and Storage
Best stored desiccated at -20 degree C or below. Stable for 6 months after receipt. However, the enzyme is also stored as a refrigerated dry powder or frozen in aqueous solution.

Application Data

(Structure of AAA14843RNase A, Pancreatic Ribonuclease, Rib 1; Ribonuclease A Family 1; Ribonuclease Pancreatic; Ribonuclease RNase A Family 1; Ribonuclease RNase A Family 1 Pancreatic; RNAseA; RNase 1; RNASE1; RNS1)

product-image-AAA14843_APP.jpg Application Data (Structure of AAA14843RNase A, Pancreatic Ribonuclease, Rib 1; Ribonuclease A Family 1; Ribonuclease Pancreatic; Ribonuclease RNase A Family 1; Ribonuclease RNase A Family 1 Pancreatic; RNAseA; RNase 1; RNASE1; RNS1)
Related Product Information for RNASE1 enzyme
Ribonuclease A is used to isolate DNA for RNA-free DNA. Ribonuclease A hydrolyzes RNA at C and U residues, cleaving between the 3’-Phosphate group of a pyrimidine nucleotide and the 5’-hydroxyl group of the adjacent nucleotide, i.e., those cleaving cyclic 2',3'-pyrimidine nucleotide residues either singly or at the termination of purine nucleotide chains (Volkin and Cohn 1953). The composition and structure of ribonuclease A has been extensively investigated. The tertiary structure was reported by Kartha, et al. (1967) and Lin, (1970). Wang, et al. (1975) indicate that flexibility in a three-dimensional structure is essential for optimal catalytic activity.
Product Categories/Family for RNASE1 enzyme

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13.7kD
NCBI Official Full Name
ribonuclease pancreatic
NCBI Official Synonym Full Names
ribonuclease, RNase A family, 1 (pancreatic)
NCBI Official Symbol
RNASE1
NCBI Official Synonym Symbols
RIB1; RNS1
NCBI Protein Information
ribonuclease pancreatic; RIB-1; RNase 1; RNase A; HP-RNase; RNase upI-1; ribonuclease 1; ribonuclease A
UniProt Protein Name
Ribonuclease pancreatic
UniProt Gene Name
RNASE1
UniProt Synonym Gene Names
RIB1; RNS1; RNase 1; RNase A
UniProt Entry Name
RNAS1_HUMAN

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Product Notes

The RNASE1 rnase1 (Catalog #AAA14843) is an Enzyme and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Ribonuclease A, Bovine Pancreas, Enzyme" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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