Leutenizing hormone Releasing Hormone Synthetic Protein | LHRH synthetic protein
Human Leutenizing hormone Releasing Hormone (Gonadorelin)
Gene Names
GNRH1; GRH; GNRH; HH12; LHRH; LNRH
Purity
Greater than 98.0% as determined by RP-HPLC.
Synonyms
Leutenizing hormone Releasing Hormone; N/A; Human Leutenizing hormone Releasing Hormone (Gonadorelin); LHRH Human; Luteinizing Hormone Releasing Hormone Human; Progonadoliberin-1; Progonadoliberin I; LHRH; GRH; GNRH; LNRH; LHRH synthetic protein
Host
Escherichia Coli
Purity/Purification
Greater than 98.0% as determined by RP-HPLC.
Form/Format
The LHRH was lyophilized from a concentrated (1 mg/ml) solution with no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Sequence Length
92
Solubility
It is recommended to reconstitute the lyophilized LHRH in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. The LHRH is also soluble in a 1% glacial acetic acid.
Preparation and Storage
Lyophilized LHRH although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution LNRH should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Related Product Information for LHRH synthetic protein
Description: Lutenizing Hormone Releasing Hormone Human Synthetic is a single, non-glycosylated, polypeptide chain containing 10 amino acids and having a molecular mass of 1182..3 Dalton. The molecular formula is C55H75N17O13C2H4O2. The CAS Number is 71447-49-9.
Introduction: Gonadotropin-releasing hormone 1 (GNRH1), also known as Luteinising-hormone releasing hormone (LHRH), is a peptide hormone responsible for the release of FSH and LH from the anterior pituitary. GNRH1 is synthesized and released by the hypothalamus.At the pituitary, GNRH1 stimulates the synthesis and secretion of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These processes are controlled by the size and frequency of GNRH1 pulses, as well as by feedback from androgens and estrogens. Low requency GNRH1 pulses lead to FSH release, whereas high frequency GNRH1 pulses stimulate LH release.There are differences in GNRH1 secretion between males and females. In males, GNRH1 is secreted in pulses at a constant frequency, but in females the frequency of the pulses varies during the menstrual cycle and there is a large surge of GNRH1 just before ovulation.GNRH1 secretion is pulsatile in all vertebrates, and is necessary for correct reproductive function. Thus, a single hormone, GNRH1, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male.
Introduction: Gonadotropin-releasing hormone 1 (GNRH1), also known as Luteinising-hormone releasing hormone (LHRH), is a peptide hormone responsible for the release of FSH and LH from the anterior pituitary. GNRH1 is synthesized and released by the hypothalamus.At the pituitary, GNRH1 stimulates the synthesis and secretion of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These processes are controlled by the size and frequency of GNRH1 pulses, as well as by feedback from androgens and estrogens. Low requency GNRH1 pulses lead to FSH release, whereas high frequency GNRH1 pulses stimulate LH release.There are differences in GNRH1 secretion between males and females. In males, GNRH1 is secreted in pulses at a constant frequency, but in females the frequency of the pulses varies during the menstrual cycle and there is a large surge of GNRH1 just before ovulation.GNRH1 secretion is pulsatile in all vertebrates, and is necessary for correct reproductive function. Thus, a single hormone, GNRH1, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,380 Da
NCBI Official Full Name
progonadoliberin-1 isoform 2 preproprotein
NCBI Official Synonym Full Names
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
NCBI Official Symbol
GNRH1
NCBI Official Synonym Symbols
GRH; GNRH; HH12; LHRH; LNRH
NCBI Protein Information
progonadoliberin-1; GnRH-associated peptide 1; gonadotropin-releasing hormone 1 (leutinizing-releasing hormone); luliberin I; progonadoliberin I; prolactin release-inhibiting factor
UniProt Protein Name
Progonadoliberin-1
UniProt Gene Name
GNRH1
UniProt Synonym Gene Names
GNRH; GRH; LHRH; GnRH-I; LH-RH I
UniProt Entry Name
GON1_HUMAN
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Product Notes
The LHRH gnrh1 (Catalog #AAA38354) is a Synthetic Protein produced from Escherichia Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Pyr-His-Tr p-Ser-Tyr- Gly-Leu-Ar g-Pro-Gly- NH2. It is sometimes possible for the material contained within the vial of "Leutenizing hormone Releasing Hormone, Synthetic Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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