FGF23 recombinant protein
FGF23 protein
Gene Names
FGF23; ADHR; FGFN; HYPF; HPDR2; PHPTC
Purity
> 95% pure
Synonyms
FGF23; N/A; FGF23 protein; FGF-23 protein; FGF-23; FGF 23; Fibroblast Growth Factor-23 protein; FGF 23 protein; FGF23 recombinant protein
Purity/Purification
> 95% pure
Form/Format
Lyophilized powder from 10mM sodium acetate, pH 6.0 plus 0.1M arginine. Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5 mg/ml. Do not vortex.
Concentration
20ug lyophilized (varies by lot)
Sequence
Region of FGF23 protein corresponding to amino acids MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI.
Sequence Length
251
Source
E.coli
Species
Human
Grade
Recombinant
Contaminants
Endotoxin: <0.1ng/ug
Biological Significance
The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF23, FGF21 and FGF19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1.
Biohazrd
Use appropriate laboratory precautions when handling this product.
Preparation and Storage
Ships ambient or refrigerated. Upon receipt store at 4°C short term; -20°C to -80°C long term. Avoid repeat freeze-thaws.
Related Product Information for FGF23 recombinant protein
Purified recombinant Human FGF23 protein
Product Categories/Family for FGF23 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
22.5 kDa
NCBI Official Full Name
fibroblast growth factor 23
NCBI Official Synonym Full Names
fibroblast growth factor 23
NCBI Official Symbol
FGF23
NCBI Official Synonym Symbols
ADHR; FGFN; HYPF; HPDR2; PHPTC
NCBI Protein Information
fibroblast growth factor 23
UniProt Protein Name
Fibroblast growth factor 23
UniProt Gene Name
FGF23
UniProt Synonym Gene Names
HYPF; FGF-23
UniProt Entry Name
FGF23_HUMAN
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Product Notes
The FGF23 fgf23 (Catalog #AAA75595) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Region of FGF23 protein correspond ing to amino acids MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI. It is sometimes possible for the material contained within the vial of "FGF23, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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