SDS-PAGE
(Figure 1. Human FLT3 Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
FLT3 Ligand Recombinant Protein | FLT3 recombinant protein
Recombinant human FLT3 Ligand protein with C-terminal mouse Fc and 6xHis tag
Gene Names
FLT3LG; FL; FLT3L
Applications
ELISA, Western Blot
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
FLT3 Ligand; N/A; Recombinant human FLT3 Ligand protein with C-terminal mouse Fc and 6xHis tag; Human FLT3 Ligand Protein, mFc-His Tag; FLT3LG; FL; FLT3L; Flt3 ligand; FLT3 recombinant protein
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-40% trehalose is added as protectants before lyophilization.
Sequence
FLT3 Ligand(Thr27-Pro185)+mFc(Pro99-Lys330)
Applicable Applications for FLT3 recombinant protein
ELISA, WB (Western Blot)
Source
Human
Conjugation
C-Mouse Fc and 6xHis tag
Reconstitution
Reconstitute with deionized water
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice
Shipping: Blue Ice
SDS-PAGE
(Figure 1. Human FLT3 Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
SDS-PAGE
(Figure 1. Human FLT3 Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
ELISA
(Figure 1. Human FLT3 Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
ELISA
(Figure 1. Human FLT3 Ligand Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
Related Product Information for FLT3 recombinant protein
FMS-like tyrosine kinase 3 ligand (Flt-3 Ligand) is also known as FL, Flt3L and FLT3LG, is an alpha-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. FLT3LG is expressed as a noncovalentlylinked dimer by T cells and bone marrow and thymic fibroblasts. Each 36kDa chain carries approximately 12kDa of N-and O-linked carbohydrates. FLT3LG is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). FLT3LG acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3LG induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation. FLT3LG cooperates with IL2, IL6, IL7, and IL15 to induce NK cell development and with IL3, IL7 and IL11 to induce terminal B cell maturation. Animal studies also show FLT3LG to reduce the severity of experimentally induced allergic inflammation. FLT3LG is crucial for steady-state pDC and cDC development. A lack of FLT3L results in low levels of DCs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,416 Da
NCBI Official Full Name
fms-related tyrosine kinase 3 ligand
NCBI Official Synonym Full Names
fms-related tyrosine kinase 3 ligand
NCBI Official Symbol
FLT3LG
NCBI Official Synonym Symbols
FL; FLT3L
NCBI Protein Information
fms-related tyrosine kinase 3 ligand; flt3 ligand
UniProt Protein Name
Fms-related tyrosine kinase 3 ligand
UniProt Gene Name
FLT3LG
UniProt Synonym Gene Names
Flt3 ligand; Flt3L
UniProt Entry Name
FLT3L_HUMAN
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Product Notes
The FLT3 flt3lg (Catalog #AAA47215) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FLT3 Ligand can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the FLT3 flt3lg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: FLT3 Ligand(Thr 27-Pro185) +mFc(Pro99 -Lys330). It is sometimes possible for the material contained within the vial of "FLT3 Ligand, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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