Form/Format
100ul in 10mM HEPES (pH 7.5), 150mM NaCl, 100ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western blots.
Applicable Applications for anti-GABRB2 antibody
WB (Western Blot), DB (Dot Blot)
Antibody Specificity
Specific for the ~50k to 56k Beta2-subunit of the GABAA-R in Western blots of rat brain memebrane fractions. Also recognizes the Beta2subunit of the GABAA-R in bovine, human and mouse brain extracts.
Preparation and Storage
Ships on blue ice. For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stock solutions are stable for a minimum of 1 year at -20°C.
Related Product Information for anti-GABRB2 antibody
Affinity purified rabbit polyclonal antibody
References
• McKernan RM, et al. (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor alpha1-subtype. Nature Neurosci 3:587-592.
• McKernan RM, et al. (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor alpha1-subtype. Nature Neurosci 3:587-592.
• Ogris W, Pöltl A, Hauer B, Ernst M, Oberto A, Wulff P, Höger H, Wisden W, Sieghart W (2004) Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor gamma2-subunit. Biochem Pharmacol 68:1621-1629
• Olsen RW, Tobin AJ (1990) Molecular biology of GABAA receptors. FASEB 4:1469-1480.
• Pöltl A, Hauer B, Fuchs K, Tretter V, Sieghart W (2003) Subunit composition and quantitative importance of GABAA receptor subtypes in the cerebellum of mouse and rat. J Neurochem 87:1444-1455.
• McKernan RM, et al. (2000) Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor alpha1-subtype. Nature Neurosci 3:587-592.
• Ogris W, Pöltl A, Hauer B, Ernst M, Oberto A, Wulff P, Höger H, Wisden W, Sieghart W (2004) Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABAA receptor gamma2-subunit. Biochem Pharmacol 68:1621-1629
• Olsen RW, Tobin AJ (1990) Molecular biology of GABAA receptors. FASEB 4:1469-1480.
• Pöltl A, Hauer B, Fuchs K, Tretter V, Sieghart W (2003) Subunit composition and quantitative importance of GABAA receptor subtypes in the cerebellum of mouse and rat. J Neurochem 87:1444-1455.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit beta-2
NCBI Official Synonym Full Names
gamma-aminobutyric acid (GABA) A receptor, beta 2
NCBI Official Symbol
Gabrb2
NCBI Official Synonym Symbols
GARB2
NCBI Protein Information
gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2; Gamma-aminobutyric acid receptor beta 2; gamma-aminobutyric acid receptor, subunit beta 2; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 2
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit beta-2
UniProt Gene Name
Gabrb2
UniProt Synonym Gene Names
Gabrb-2
UniProt Entry Name
GBRB2_RAT
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Product Notes
The GABRB2 gabrb2 (Catalog #AAA72790) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GABAA Receptor beta2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), DB (Dot Blot). Researchers should empirically determine the suitability of the GABRB2 gabrb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABAA Receptor beta2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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