Standard Curve (Sample)
General Sorbitol Dehydrogenase Assay Kit | SORD assay kit
Sorbitol Dehydrogenase Microplate Assay Kit
Gene Names
SORD; SORD1; HEL-S-95n
Reactivity
General
Applications
Functional Assay
Synonyms
Sorbitol Dehydrogenase; N/A; Sorbitol Dehydrogenase Microplate Assay Kit; EC 1.1.1.14; Sorbitol dehydrogenase; SDH; SORD; L-iditol 2-dehydrogenase; Glucitol dehydrogenase; Polyol dehydrogenase; SORD assay kit
Reactivity
General
Sequence Length
357
Samples
Urine, serum, plasma, tissue extracts, cell lysate, cell culture media and other biological fluids samples
Detection Range
4 umol/L - 400 umol/L
Applicable Applications for SORD assay kit
FA (Functional Assay)
Preparation and Storage
Shipped and store at 4 degree C for 6 months.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for SORD assay kit
Background/Introduction: Sorbitol dehydrogenase (SDH), found in organisms from bacteria to humans, converts sorbitol, the sugar alcohol form of glucose, to fructose, and the zinc-dependent reaction uses NAD+ as a cofactor. Organs abundant in SDH activity include the liver, kidney, lens and seminal vesicle. SDH and aldose reductase (AR) form the polyol pathway that interconverts glucose and fructose. Since SDH activity promotes the formation of NADH, the redox change induced by elevated SDH may have a pathogenic role in certain disease state, making SDH a potential therapeutic target. In addition, SDH has a close evolutionary relationship with alcohol dehydrogenase (ADH). The assay is initiated with the enzymatic hydrolysis of the sorbitol by sorbitol dehydrogenase. The enzyme catalysed reaction products NADH, can be measured at a colorimetric readout at 340 nm.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,812 Da
NCBI Official Full Name
sorbitol dehydrogenase
NCBI Official Synonym Full Names
sorbitol dehydrogenase
NCBI Official Symbol
SORD
NCBI Official Synonym Symbols
SORD1; HEL-S-95n
NCBI Protein Information
sorbitol dehydrogenase
UniProt Protein Name
Sorbitol dehydrogenase
UniProt Gene Name
SORD
UniProt Entry Name
DHSO_HUMAN
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Product Notes
The General SORD sord (Catalog #AAA261593) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA261593 Assay Kit recognizes General SORD. AAA Biotech's Sorbitol Dehydrogenase can be used in a range of immunoassay formats including, but not limited to, FA (Functional Assay). Researchers should empirically determine the suitability of the SORD sord for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sorbitol Dehydrogenase, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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