General Anti PEG antibody ELISA Kit | PEG elisa kit
Anti PEG antibody ELISA (Mouse IgG specific)
Reactivity
General
Synonyms
Anti PEG antibody; N/A; Anti PEG antibody ELISA (Mouse IgG specific); PEG elisa kit
Reactivity
General
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store kit components at -20 degree C unless specified otherwise. Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Related Product Information for PEG elisa kit
Background: Polyethylene glycol (PEG) chains are often used to modify therapeutic biologic agents in order to prolong the circulating half-life of the modified protein by slowing proteolytic degradation. It has been reported that repeat injections of PEGylated proteins can induce anti-PEG antibodies. Anti-PEG antibodies can result in rapid clearance and decreased drug efficacy (accelerated blood clearance, or ABC, phenomenon).
Principle of the Assay: This immunogenicity assay uses the direct ELISA technique. The supplied 96 well microplate is pre-coated with PEG. Quality control and test samples are pipetted into the appropriate wells. Anti-PEG antibodies bind the immobilized PEG. After washing, detection antibody (antimouse IgG Peroxidase) is added. Any unbound antibodyenzyme reagent is removed with a final wash and a substrate solution is added to the wells for color development. Color development is proportional to the amount of anti-PEG IgG.
Principle of the Assay: This immunogenicity assay uses the direct ELISA technique. The supplied 96 well microplate is pre-coated with PEG. Quality control and test samples are pipetted into the appropriate wells. Anti-PEG antibodies bind the immobilized PEG. After washing, detection antibody (antimouse IgG Peroxidase) is added. Any unbound antibodyenzyme reagent is removed with a final wash and a substrate solution is added to the wells for color development. Color development is proportional to the amount of anti-PEG IgG.
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Product Notes
The General PEG (Catalog #AAA59620) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA59620 ELISA Kit recognizes General PEG. It is sometimes possible for the material contained within the vial of "Anti PEG antibody, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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