Glial fibrillary acidic protein Recombinant Protein | GFAP recombinant protein

Recombinant Mouse Glial fibrillary acidic protein (Gfap)

Cat. Num. AAA18409

• Gene Names: Gfap; AI836096
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Glial fibrillary acidic protein; Recombinant Mouse Glial fibrillary acidic protein (Gfap); GFAP recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-430aa; Full Length Protein
• Sequence: MERRRITSARRSYASETVVRGLGPSRQLGTMPRFSLSRMTPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNFAQDLGTLRQKLQDETNLRLEAENNLAAYRQEADEATLARVDLERKVESLEEEIQFLRKIYEEEVRELREQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKDSKQEHKDVVM

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for GFAP recombinant protein

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

References

Structure of the mouse glial fibrillary acidic protein gene implications for the evolution of the intermediate filament multigene family.Balcarek J.M., Cowan N.J.Nucleic Acids Res. 13:5527-5543(1985) Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) Sheng J., Wu X., Lin F., Yang X., Deng J. Identification of two N-terminal non-alpha-helical domain motifs important in the assembly of glial fibrillary acidic protein.Ralton J.E., Lu X., Hutcheson A.M., Quinlan R.A.J. Cell Sci. 107:1935-1948(1994) Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein structural conservation of intermediate filaments.Lewis S.A., Balcarek J.M., Krek V., Shelanski M., Cowan N.J.Proc. Natl. Acad. Sci. U.S.A. 81:2743-2746(1984) Structural implications of a cDNA clone encoding mouse glial fibrillary acidic protein.Cowan N.J., Lewis S.A., Balcarek J.M., Krek V., Shelanski M.L.Ann. N. Y. Acad. Sci. 455:575-582(1985) Characterization of human cDNA and genomic clones for glial fibrillary acidic protein.Brenner M., Lampel K., Nakatani Y., Mill J., Banner C., Mearow K., Dohadwala M., Lipsky R., Freese E.Brain Res. Mol. Brain Res. 7:277-286(1990) High-throughput sequence identification of gene coding variants within alcohol-related QTLs.Ehringer M.A., Thompson J., Conroy O., Xu Y., Yang F., Canniff J., Beeson M., Gordon L., Bennett B., Johnson T.E., Sikela J.M.Mamm. Genome 12:657-663(2001) Novel metastatic mouse tumor cells express multiple properties of macrophages.Huysentruyt L.C., Banerjee D., Seyfried T.N. Lubec G., Klug S., Kang S.U. Lubec G., Sunyer B., Chen W.-Q.Submitted (JAN-2009) to UniProtKB Genetic polymorphism and sequence evolution of an alternatively spliced exon of the glial fibrillary acidic protein gene, GFAP.Singh R., Nielsen A.L., Johansen M.G., Jorgensen A.L.Genomics 82:185-193(2003) A new splice variant of glial fibrillary acidic protein GFAPepsilon, interacts with the presenilin proteins.Nielsen A.L., Holm I.E., Johansen M., Bonven B., Jorgensen P., Jorgensen A.L.J. Biol. Chem. 277:29983-29991(2002) Comprehensive identification of phosphorylation sites in postsynaptic density preparations.Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.Mol. Cell. Proteomics 5:914-922(2006) Synemin is expressed in reactive astrocytes in neurotrauma and interacts differentially with vimentin and GFAP intermediate filament networks.Jing R., Wilhelmsson U., Goodwill W., Li L., Pan Y., Pekny M., Skalli O.J. Cell Sci. 120:1267-1277(2007)

NCBI and Uniprot Product Information

• NCBI GI #: 196115327
• NCBI GeneID: 14580
• NCBI Accession #: NP_001124492.1
• NCBI GenBank Nucleotide #: NM_001131020.1
• UniProt Accession #: P03995; Q09J71; Q3USS4; Q496R4; Q496S3; Q7TQ30; Q80VX6; Q925K2; Q925K3; A1E2H7; A2AH87; B2RTI7
• Molecular Weight: 51.9 kDa
• NCBI Official Full Name: glial fibrillary acidic protein isoform 1
• NCBI Official Synonym Full Names: glial fibrillary acidic protein
• NCBI Official Symbol: Gfap
• NCBI Official Synonym Symbols: AI836096
• UniProt Protein Name: Glial fibrillary acidic protein
• UniProt Gene Name: Gfap
• UniProt Synonym Gene Names: GFAP
• UniProt Entry Name: GFAP_MOUSE