IHC (Immunohiostchemistry)
(GluR4 staining of human brain tissue, cortex (formalin-fixed paraffin-embedded) at 5 ug/ml followed by biotinylated horse anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Protocol on data-sheet.)
Goat GluR4/AMPA4 Antibody | anti-GluR4/AMPA4 antibody
GluR4/AMPA4
Gene Names
GRIA4; GLUR4; GLURD; GluA4; GLUR4C; NEDSGA
Reactivity
Human, Mouse, Rat, Bovine
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
GluR4/AMPA4; N/A; anti-GluR4/AMPA4 antibody
Host
Goat
Reactivity
Human, Mouse, Rat, Bovine
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
Liquid
Sequence Length
902
Applicable Applications for anti-GluR4/AMPA4 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Synthetic peptide: C-KKLDQREYPGSETP, from the internal region of the protein sequence according to NP_000820.3; NP_001070711.1; NP_001070712.1.
IHC (Immunohiostchemistry)
(GluR4 staining of human brain tissue, cortex (formalin-fixed paraffin-embedded) at 5 ug/ml followed by biotinylated horse anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Protocol on data-sheet.)
IHC (Immunohiostchemistry)
(GluR4 staining of human brain tissue, cortex (formalin-fixed paraffin-embedded) at 5 ug/ml followed by biotinylated horse anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Protocol on data-sheet.)
IHC (Immunohistochemistry)
(GluR4 (0.3ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
IHC (Immunohistochemistry)
(GluR4 (0.3ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-GluR4/AMPA4 antibody
Human glutamate receptor 4 (GRIA4) is a new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. Binding studies showed that human GluR4 transfected into simian kidney cells (COS-1) exhibits high specific binding for[3H](RS)-alpha-amino- 3-hydroxy-5-methylisoxazole-4-propionic acid ([3H]AMPA) but not [3H]kainate. Ion substitution experiments indicate that hGluR4 receptor-linked ion channels in their homomeric state are permeable to both CA2+ and Na+ ions. Immunoprecipitation studies suggest that GRIA1 exists in situ in the form of a pentamer.
Nociceptors, involved primarily in the mediation of neuropathic pain, may be presynaptically modulated by GluR4-containing AMPA receptors.
Nociceptors, involved primarily in the mediation of neuropathic pain, may be presynaptically modulated by GluR4-containing AMPA receptors.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
glutamate receptor 4 isoform 1
NCBI Official Synonym Full Names
glutamate ionotropic receptor AMPA type subunit 4
NCBI Official Symbol
GRIA4
NCBI Official Synonym Symbols
GLUR4; GLURD; GluA4; GLUR4C; NEDSGA
NCBI Protein Information
glutamate receptor 4
UniProt Protein Name
Glutamate receptor 4
UniProt Gene Name
GRIA4
UniProt Synonym Gene Names
GLUR4; GluR-4; GluR4; GluA4
UniProt Entry Name
GRIA4_HUMAN
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Product Notes
The GluR4/AMPA4 gria4 (Catalog #AAA76600) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The GluR4/AMPA4 reacts with Human, Mouse, Rat, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's GluR4/AMPA4 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GluR4/AMPA4 gria4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GluR4/AMPA4, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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