Activity
(The ED(50) was determined by the dose-dependent proliferation of human MCF-7 cells was found to be )
Glial growth factor (GGF2) Active Protein | GGF2 active protein
Human Glial growth factor (GGF2) Recombinant
Purity
>95%, as determined by SDS-PAGE
Synonyms
Glial growth factor (GGF2); N/A; Human Glial growth factor (GGF2) Recombinant; Human Glial growth factor (GGF2) Recombinant ; egf; ggf2; nrg1; nrg-1; glial; heregulin; hrg; GGF2 active protein
Host
HEK cells
Purity/Purification
>95%, as determined by SDS-PAGE
Form/Format
Recombinant Human GGF2 is supplied as lyophilized 0.2 um filtered PBS solution, pH7.2.
Host Note
Optimized DNA sequence encoding Human Neuregulin-1 isoform 9, GGF2 was expressed in HEK cells.
Endotoxin
Endotoxin content was assayed using a LAL gel clot method.
Endotoxin level was found to be less than 0.1 ng/ug(1EU/ug).
Endotoxin level was found to be less than 0.1 ng/ug(1EU/ug).
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Preparation and Storage
Store lyophilized at -20°C (Long term) or at ambient temperature (Short term).
After Reconstitution store at 2-8°C (short term) or Reconstituted at -20°C for 12 months.
*For long term storage we recommend the addition of a carrier protein at 0.1%.
*Avoid repeated freeze / thaw cycles.
After Reconstitution store at 2-8°C (short term) or Reconstituted at -20°C for 12 months.
*For long term storage we recommend the addition of a carrier protein at 0.1%.
*Avoid repeated freeze / thaw cycles.
Activity
(The ED(50) was determined by the dose-dependent proliferation of human MCF-7 cells was found to be )
Activity
(The ED(50) was determined by the dose-dependent proliferation of human MCF-7 cells was found to be )
Product Categories/Family for GGF2 active protein
References
Schwann Cell Isolation and Culture Reveals the Plasticity of These Glia. David E. Weinstein (2017)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Recombinant human GGF2 (Glial growth factor) is a monomeric protein consisting of 422 amino acid residue subunits, and migrates as an approximately 66 kDa protein under non-reducing and reducing conditions in SDS-PAGE.
NCBI Official Full Name
pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c
UniProt Protein Name
Pro-neuregulin-1, membrane-bound isoform
UniProt Gene Name
NRG1
UniProt Synonym Gene Names
GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG
UniProt Entry Name
NRG1_HUMAN
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Product Notes
The GGF2 nrg1 (Catalog #AAA14429) is an Active Protein produced from HEK cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Glial growth factor (GGF2), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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