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IFN-omega active protein

Recombinant human IFN-omega protein

Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
IFN-omega; N/A; Recombinant human IFN-omega protein; interferon omega-1; interferon alpha-II-1; interferon omega 1; IFNW1; IFN-omega 1; IFN-omega active protein
Ordering
Host
HEK293
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid in. Phosphate-Buffered Saline (pH7.4) containing 10% glycerol
Concentration
1mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence Positions
22-195aa
Sequence
Leu 22
LGCDLPQNHG LLSRNTLVLL HQMRRISPFL CLKDRRDFRF PQEMVKGSQL QKAHVMSVLH EMLQQIFSLF HTERSSAAWN MTLLDQLHTG LHQQLQHLET CLLQVVGEGE SAGAISSPAL TLRRYFQGIR VYLKEKKYSD CAWEVVRMEI MKSLFLSTNM QERLRSKDRD LGSS
Applicable Applications for IFN-omega active protein
Bioactivity, SDS-PAGE
Species
Human
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Tag
His-Tag
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Related Product Information for IFN-omega active protein
IFN-omega, also known as interferon-omega, is a member of a family of proteins with antiviral, growth inhibitory and immunomodulatory activity. Type I IFNs consist of IFN alpha, beta, tau, and omega and bind to the type I IFN receptor, whereas IFN-gamma is the only type II IFN and is specific for the type II IFN receptor. IFN-omega is produced primarily in leukocytes in response to viral infection, and it has biological activities. Also, it was reported that IFN-omega could inhibit the growth of human tumors in vivo. Recombinant human IFN-omega, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques.
Product Categories/Family for IFN-omega active protein
References
Seo Y., et al, (2011) Pharmacology. 87:224-231.
Adolf G.R., et al, (1991). Biochim. Biophys. Acta.1089:167-174.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,319 Da
NCBI Official Full Name
interferon omega-1
NCBI Official Synonym Full Names
interferon, omega 1
NCBI Official Symbol
IFNW1
NCBI Protein Information
interferon omega-1; IFN-omega 1, interferon omega-1; interferon alpha-II-1
UniProt Protein Name
Interferon omega-1
UniProt Gene Name
IFNW1
UniProt Entry Name
IFNW1_HUMAN

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Product Notes

The IFN-omega ifnw1 (Catalog #AAA48989) is an Active Protein produced from HEK293 and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-195aa. AAA Biotech's IFN-omega can be used in a range of immunoassay formats including, but not limited to, Bioactivity, SDS-PAGE. Researchers should empirically determine the suitability of the IFN-omega ifnw1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Leu 22 LGCD LPQNHG LLSRNTLVLL HQMRRISPFL CLKDRRDFRF PQEMVKGSQL QKAHVMSVLH EMLQQIFSLF HTERSSAAWN MTLLDQLHTG LHQQLQHLET CLLQVVGEGE SAGAISSPAL TLRRYFQGIR VYLKEKKYSD CAWEVVRMEI MKSLFLSTNM QERLRSKDRD LGSS. It is sometimes possible for the material contained within the vial of "IFN-omega, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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