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product-image-AAA47216_SDS_PAGE13.jpg SDS-PAGE (Figure 1. Human BCMA, mFc Tag on SDS-PAGE under reducing condition.)

BCMA active protein

Recombinant human BCMA protein with C-terminal mouse Fc tag

Gene Names
TNFRSF17; BCM; BCMA; CD269; TNFRSF13A
Applications
ELISA, Western Blot
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
BCMA; N/A; Recombinant human BCMA protein with C-terminal mouse Fc tag; Human BCMA Protein, mFc Tag; TNFRSF17; CD269; BCM; BCMA active protein
Ordering
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-42% trehalose is added as protectants before lyophilization.
Sequence
BCMA(Met1-Ala54)+mFc(Pro99-Lys330)
Applicable Applications for BCMA active protein
ELISA, WB (Western Blot)
Source
Human
Biological Activity
EC50=3.163
Conjugation
C-Mouse Fc tag
Reconstitution
Reconstitute with deionized water
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
Shipping: Blue Ice

SDS-PAGE

(Figure 1. Human BCMA, mFc Tag on SDS-PAGE under reducing condition.)

product-image-AAA47216_SDS_PAGE13.jpg SDS-PAGE (Figure 1. Human BCMA, mFc Tag on SDS-PAGE under reducing condition.)

ELISA

(Figure 1. Human BCMA, mFc Tag on SDS-PAGE under reducing condition.)

product-image-AAA47216_ELISA15.png ELISA (Figure 1. Human BCMA, mFc Tag on SDS-PAGE under reducing condition.)
Related Product Information for BCMA active protein
B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
608
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,843 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 17
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 17
NCBI Official Symbol
TNFRSF17
NCBI Official Synonym Symbols
BCM; BCMA; CD269; TNFRSF13A
NCBI Protein Information
tumor necrosis factor receptor superfamily member 17; B cell maturation antigen; B-cell maturation factor; B-cell maturation protein
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 17
UniProt Gene Name
TNFRSF17
UniProt Synonym Gene Names
BCM; BCMA
UniProt Entry Name
TNR17_HUMAN

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Product Notes

The BCMA tnfrsf17 (Catalog #AAA47216) is an Active Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BCMA can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the BCMA tnfrsf17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: BCMA(Met1- Ala54)+mFc (Pro99-Lys 330). It is sometimes possible for the material contained within the vial of "BCMA, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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