Application Data
(Immobilized recombinant human IL4R at 2 ug/mL (100 uL/well) can bind recombinant human IL4. The ED50 of recombinant human IL4R is 2-4 ng/mL.)
IL4R/CD124 Active Protein | IL4R active protein
Recombinant Human IL4R/CD124 Protein
Gene Names
IL4R; CD124; IL4RA; IL-4RA
Purity
>87% by SDS-PAGE.
Synonyms
IL4R/CD124; N/A; Recombinant Human IL4R/CD124 Protein; CD124; IL-4RA; IL4RA; IL4R active protein
Host
HEK293 Cells
Purity/Purification
>87% by SDS-PAGE.
Form/Format
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
Sequence Length
825
Species
Human
Endotoxin
< 0.1 EU/ug of the protein by LAL method.
Biological Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL4R at 2 ug/mL (100 uL/well) can bind recombinant human IL4. The ED50 of recombinant human IL4R is 2-4 ng/mL.
Reconstitution
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
Tag
C-6xHis
Preparation and Storage
Store the lyophilized protein at -20 degree C to -80 degree C for long term.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
Avoid repeated freeze-thaw cycles.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
Avoid repeated freeze-thaw cycles.
Application Data
(Immobilized recombinant human IL4R at 2 ug/mL (100 uL/well) can bind recombinant human IL4. The ED50 of recombinant human IL4R is 2-4 ng/mL.)
Application Data
(Immobilized recombinant human IL4R at 2 ug/mL (100 uL/well) can bind recombinant human IL4. The ED50 of recombinant human IL4R is 2-4 ng/mL.)
SDS-PAGE
(Recombinant Human IL4R/CD124 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 42-52kDa.)
SDS-PAGE
(Recombinant Human IL4R/CD124 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 42-52kDa.)
Related Product Information for IL4R active protein
Description: Recombinant Human IL4R/CD124 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-His232) of human IL4R/CD124 (Accession #NP_000409.1) fused with a 6xHis tag at the C-terminus.
Background: This protein is alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.
Background: This protein is alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.
Product Categories/Family for IL4R active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
interleukin-4 receptor subunit alpha isoform a
NCBI Official Synonym Full Names
interleukin 4 receptor
NCBI Official Symbol
IL4R
NCBI Official Synonym Symbols
CD124; IL4RA; IL-4RA
NCBI Protein Information
interleukin-4 receptor subunit alpha
UniProt Protein Name
Interleukin-4 receptor subunit alpha
UniProt Gene Name
IL4R
UniProt Synonym Gene Names
IL4RA; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; sIL4Ralpha/prot; IL4-BP
UniProt Entry Name
IL4RA_HUMAN
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Product Notes
The IL4R il4r (Catalog #AAA281424) is an Active Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IL4R/CD124, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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