Application Data
(Recombinant mouse IL-23 and human TGF-beta1 were used to induce the mouse T cells differentiate into Th17 cells. Flow cytometry was used to detect the expression of IL-17A. Results showed that Th17 cells were induced)
Mature TGF-beta 1 Active Protein | TGF-beta1 active protein
Active Recombinant Human Mature TGF-beta 1 Protein
Lyophilized from a 0.22 um filtered solution of 50 mM Glycine, 150 mM NaCl, pH3.5.
2. Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 mouse T cells. The ED50 for this effect is 0.09-0.39 ng/mL, corresponding to a specific activity of 2.56 ^ 106~1.11^ 107 units/mg.
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Application Data
(Recombinant mouse IL-23 and human TGF-beta1 were used to induce the mouse T cells differentiate into Th17 cells. Flow cytometry was used to detect the expression of IL-17A. Results showed that Th17 cells were induced)
Application Data
(Recombinant mouse IL-23 and human TGF-beta1 were used to induce the mouse T cells differentiate into Th17 cells. Flow cytometry was used to detect the expression of IL-17A. Results showed that Th17 cells were induced)
Application Data
(Active Recombinant Human Mature TGFbeta 1 induces MCF7 cells EMT with a concentration of 12.5 ng/mL. After 10 h, the cell morphology significantly altered, appearing a fusiform shape (figure 1). After 48 h, the change of EMT associated genes are as figure 2. Results showed that the induction was successful.(Customer feedback data))
Application Data
(Active Recombinant Human Mature TGFbeta 1 induces MCF7 cells EMT with a concentration of 12.5 ng/mL. After 10 h, the cell morphology significantly altered, appearing a fusiform shape (figure 1). After 48 h, the change of EMT associated genes are as figure 2. Results showed that the induction was successful.(Customer feedback data))
Application Data
(Active Recombinant Human mature TGFbeta1 stimulates smad2/3 autophosphorylation in Human Umbilical Vein Endothelial Cells (HUVEC). 10ng/mL of Recombinant Human TGF-beta 1 can effectively enhance smad2/3 autophosphorylation.(Customer feedback data))
Application Data
(Active Recombinant Human mature TGFbeta1 stimulates smad2/3 autophosphorylation in Human Umbilical Vein Endothelial Cells (HUVEC). 10ng/mL of Recombinant Human TGF-beta 1 can effectively enhance smad2/3 autophosphorylation.(Customer feedback data))
Application Data
(Active Recombinant Human mature TGFbeta1 induces EMT in A549 cells. As the concentration of TGF-beta1 increased, the expression of epithelial cell marker E-cad significantly downregulated.(Customer feedback data))
Application Data
(Active Recombinant Human mature TGFbeta1 induces EMT in A549 cells. As the concentration of TGF-beta1 increased, the expression of epithelial cell marker E-cad significantly downregulated.(Customer feedback data))
Application Data
(Recombinant Human Mature TGFB1 inhibit the IL-4 -dependent proliferation of HT?2 mouse T cells. The ED50 for this effect is 0.09-0.39 ng/mL, corresponding to a specific activity of 2.56 × 106~1.11× 107 units/mg.)
Application Data
(Recombinant Human Mature TGFB1 inhibit the IL-4 -dependent proliferation of HT?2 mouse T cells. The ED50 for this effect is 0.09-0.39 ng/mL, corresponding to a specific activity of 2.56 × 106~1.11× 107 units/mg.)
Application Data
(Immobilized Human TGF-beta 1 at 2 ug/mL (100 uL/well) can bind Human TGFBR2 with a linear range of 0.78-11 ng/mL.)
Application Data
(Immobilized Human TGF-beta 1 at 2 ug/mL (100 uL/well) can bind Human TGFBR2 with a linear range of 0.78-11 ng/mL.)
SDS-PAGE
(Active Recombinant Human Mature TGFbeta 1 Protein was determined by SDSPAGE with Coomassie Blue, showing a band at 14kDa.)
SDS-PAGE
(Active Recombinant Human Mature TGFbeta 1 Protein was determined by SDSPAGE with Coomassie Blue, showing a band at 14kDa.)
NCBI and Uniprot Product Information
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Product Notes
The TGF-beta1 tgfb1 (Catalog #AAA28445) is an Active Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Mature TGF-beta 1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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