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product-image-AAA129486_SDS_PAGE13.jpg SDS-PAGE (Figure 2. Human ACKR1-Strep-Nanodisc, C-DYKDDDDK&Strep Tag on SDS-PAGE)

ACKR1 protein

Human ACKR1-Strep full length protein-synthetic nanodisc

Gene Names
DARC; FY; Dfy; GPD; GpFy; CCBP1; CD234; WBCQ1
Synonyms
ACKR1; N/A; Human ACKR1-Strep full length protein-synthetic nanodisc; CCBP1; CD234; DARC; DARC/ACKR1; Dfy; FY; GPD; GpFy; WBCQ1; ACKR1 protein
Ordering
Host
HEK293
Form/Format
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5%-8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower
Tag
C-DYKDDDDK&Strep
Preparation and Storage
Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

SDS-PAGE

(Figure 2. Human ACKR1-Strep-Nanodisc, C-DYKDDDDK&Strep Tag on SDS-PAGE)

product-image-AAA129486_SDS_PAGE13.jpg SDS-PAGE (Figure 2. Human ACKR1-Strep-Nanodisc, C-DYKDDDDK&Strep Tag on SDS-PAGE)

ELISA

(Figure 1. Elisa plates were pre-coated with C-DYKDDDDK&Strep Tag ACKR1-Strep-Nanodisc (0.2ug/per well). Serial diluted anti-DYKDDDDK monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-DYKDDDDK monoclonal antibody binding with ACKR1-Strep-nanodisc is 11.96ng/ml.)

product-image-AAA129486_ELISA15.jpg ELISA (Figure 1. Elisa plates were pre-coated with C-DYKDDDDK&Strep Tag ACKR1-Strep-Nanodisc (0.2ug/per well). Serial diluted anti-DYKDDDDK monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-DYKDDDDK monoclonal antibody binding with ACKR1-Strep-nanodisc is 11.96ng/ml.)
Related Product Information for ACKR1 protein
The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Product Categories/Family for ACKR1 protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,553 Da
NCBI Official Full Name
Duffy antigen/chemokine receptor isoform a
NCBI Official Synonym Full Names
Duffy blood group, chemokine receptor
NCBI Official Symbol
DARC
NCBI Official Synonym Symbols
FY; Dfy; GPD; GpFy; CCBP1; CD234; WBCQ1
NCBI Protein Information
Duffy antigen/chemokine receptor; glycoprotein D; Fy glycoprotein; Duffy blood group antigen; plasmodium vivax receptor
UniProt Protein Name
Duffy antigen/chemokine receptor
UniProt Gene Name
DARC
UniProt Synonym Gene Names
FY; GPD; GpFy
UniProt Entry Name
DUFFY_HUMAN

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Product Notes

The ACKR1 darc (Catalog #AAA129486) is a Protein produced from HEK293 and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ACKR1, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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