Major Histocompatibility Complex Class II DR Alpha Recombinant Protein | HLA-DRA recombinant protein
Recombinant Human Major Histocompatibility Complex Class II DR Alpha
Gene Names
HLA-DRA; MLRW; HLA-DRA1
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Major Histocompatibility Complex Class II DR Alpha; N/A; Recombinant Human Major Histocompatibility Complex Class II DR Alpha; HLA-DRA Human; Major Histocompatibility Complex Class II DR Alpha Human Recombinant; Major Histocompatibility Complex; Class II; DR Alpha; HLA-DRA1; MHC Class II AntigenDRA; MLRW; Histocompatibility AntigenHLA-DR Alpha; HLAClass II Histocompatibility Antigen; DR Alpha Chain; MHC Cell Surface Glycoprotein; HLA-DRA recombinant protein
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
HLA-DRA protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MIKEEHVIIQ AEFYLNPDQS GEFMFDFDGD EIFHVDMAKK ETVWRLEEFG RFASFEAQGALANIAVDKAN LEIMTKRSNY TPITNVPPEV TVLTNSPVEL REPNVLICFI DKFTPPVVNV TWLRNGKPVTTGVSETVFLP REDHLFRKFH YLPFLPSTED VYDCRVEHWG LDEPLLKHWE FDAPSPLPET TE
Sequence Length
254
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Related Product Information for HLA-DRA recombinant protein
Description: HLA-DRA Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 212 amino acids (26-216 a.a) and having a molecular mass of 24.3kDa.HLA-DRA is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Major histocompatibility complex, class II, DR alpha (HLA-DRA) belongs to the MHC class II family. HLA-DRA binds peptides derived from antigens which access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for identification by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mainly by degradation of proteins which access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.
Introduction: Major histocompatibility complex, class II, DR alpha (HLA-DRA) belongs to the MHC class II family. HLA-DRA binds peptides derived from antigens which access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for identification by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mainly by degradation of proteins which access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.
Product Categories/Family for HLA-DRA recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,607 Da
NCBI Official Full Name
HLA class II histocompatibility antigen, DR alpha chain
NCBI Official Synonym Full Names
major histocompatibility complex, class II, DR alpha
NCBI Official Symbol
HLA-DRA
NCBI Official Synonym Symbols
MLRW; HLA-DRA1
NCBI Protein Information
HLA class II histocompatibility antigen, DR alpha chain; MHC cell surface glycoprotein; MHC class II antigen DRA; histocompatibility antigen HLA-DR alpha
UniProt Protein Name
HLA class II histocompatibility antigen, DR alpha chain
UniProt Gene Name
HLA-DRA
UniProt Synonym Gene Names
HLA-DRA1
UniProt Entry Name
DRA_HUMAN
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Product Notes
The HLA-DRA hla-dra (Catalog #AAA39107) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MIKEEH VIIQ AEFYLNPDQS GEFMFDFDGD EIFHVDMAKK ETVWRLEEFG RFASFEAQGA LANIAVDKAN LEIMTKRSNY TPITNVPPEV TVLTNSPVEL REPNVLICFI DKFTPPVVNV TWLRNGKPVT TGVSETVFLP REDHLFRKFH YLPFLPSTED VYDCRVEHWG LDEPLLKHWE FDAPSPLPET TE. It is sometimes possible for the material contained within the vial of "Major Histocompatibility Complex Class II DR Alpha, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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