SDS-PAGE
Haptoglobin/Zonulin Recombinant Protein | HP recombinant protein
Recombinant Human Haptoglobin/Zonulin Protein(C-6His)
Purity
> 95 % as determined by reducing SDS-PAGE.
Synonyms
Haptoglobin/Zonulin; N/A; Recombinant Human Haptoglobin/Zonulin Protein(C-6His); Haptoglobin; Zonulin; HP ; HP recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4.
Sequence
Val19-Gln160 & Ile162-Asn406
Species
Human
Reconstitution
We recommend that the vial be centrifuged to opening to bring the contents to the bottom. Do not mix by vortex. It is recommended that sterile water(200ul) be added to the vial to prepare a stock solution of 0.25mg/mL. Concentration is measured by UV-Vis.
Tag
C-6His
Endotoxin
< 1.0 EU per ug as determined by the LAL method.
Preparation and Storage
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
SDS-PAGE
SDS-PAGE
Related Product Information for HP recombinant protein
Haptoglobin(HP) is a secreted protein which is a member of the peptidase S1 family of serine proteases. As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Mol_Mass: 15.9 & 28.3 kDa
AP_Mol_Mass: 16 & 40-75 kDa
AP_Mol_Mass: 16 & 40-75 kDa
NCBI Official Full Name
haptoglobin
NCBI Official Symbol
HP
NCBI Protein Information
haptoglobin
UniProt Protein Name
Haptoglobin
UniProt Gene Name
HP
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Product Notes
The HP hp (Catalog #AAA174017) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Val19-Gln1 60 & Ile162-Asn 406. It is sometimes possible for the material contained within the vial of "Haptoglobin/Zonulin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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