Artemin Active Protein | ARTN active protein
Artemin protein
Gene Names
ARTN; EVN; NBN; ENOVIN
Purity
> 98% pure
Synonyms
Artemin; N/A; Artemin protein; EVN protein; Enovin protein; ART protein; Neublastin protein; ARTN protein; NBN protein; ARTN active protein
Host
Human
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilized powder.
Concentration
20ug lyophilized (varies by lot)
Sequence
Region of Artemin protein corresponding to amino acids AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG.
Sequence Length
237
Protein Type
Recombinant
Biological Significance
Artemin is a disulfide-linked homodimeric neurotrophic factor structurally related to GDNF, Artemin, Neurturin and Persephin. These proteins belong to the cysteine-knot superfamily of growth factors that assume stable dimeric protein structures. Artemin, GDNF, Persephin and Neurturin all signal through a multicomponent receptor system, composed of RET (receptor tyrosine kinase) and one of the four GFRalpha (alpha1-alpha4) receptors. Artemin prefers the receptor GFRalpha3-RET, but will use other receptors as an alternative. Artemin supports the survival of all peripheral ganglia such as sympathetic, neural crest and placodally derived sensory neurons, and dompaminergic midbrain neurons.
Bioactivity
Determined by it's ability to promote survival and neurite outgrowth and dorsal root ganglion neurons.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for ARTN active protein
Purified recombinant Human Artemin protein
Product Categories/Family for ARTN active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
24.4 kDa
NCBI Official Full Name
Artemin
NCBI Official Synonym Full Names
artemin
NCBI Official Symbol
ARTN
NCBI Official Synonym Symbols
EVN; NBN; ENOVIN
NCBI Protein Information
artemin
UniProt Protein Name
Artemin
UniProt Gene Name
ARTN
UniProt Synonym Gene Names
EVN
UniProt Entry Name
ARTN_HUMAN
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Product Notes
The ARTN artn (Catalog #AAA75568) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Region of Artemin protein correspond ing to amino acids AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG. It is sometimes possible for the material contained within the vial of "Artemin, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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